iPTMnet Report for Q9BVC4 (MLST8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BVC4 / LST8_HUMAN
Protein Name Target of rapamycin complex subunit LST8
Gene Name Name: MLST8
Synonyms:GBL;
Organism Homo sapiens (Human)

PRO ID PR:Q9BVC4
DAG View
PRO Name target of rapamycin complex subunit LST8 (human)
Definition A target of rapamycin complex subunit LST8 that is encoded in the genome of human.
Short Label hMLST8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BVC4 (MLST8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19369195, 20068231
S4 Phosphorylation PhosphoSitePlus
T7 Phosphorylation UniProt 19369195
S43 Phosphorylation PhosphoSitePlus
T51 Phosphorylation UniProt 34741373
S55 Phosphorylation PhosphoSitePlus
Y62 Phosphorylation PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
S116 Phosphorylation RLIMS-P 29699848
C121 Methylation IEDB 31844290
T214 Phosphorylation PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
Y222 Phosphorylation PhosphoSitePlus
C244 Methylation IEDB 31844290
K245 Ubiquitination PhosphoSitePlus
K305 Sumoylation PhosphoSitePlus
K305 Ubiquitination PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T3 Phosphorylation HPRD 18691976
S4 Phosphorylation HPRD 18691976, 20068231
T214 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
M1 T1 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S43 F43 Biomuta DOID:4159 / skin cancer [ cosmic ]
K86 N86 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S116 F116 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]