iPTMnet Report for Q9BVA1 (TUBB2B)
Protein Information
UniProt AC / UniProt ID | Q9BVA1 / TBB2B_HUMAN |
Protein Name | Tubulin beta-2B chain |
Gene Name | Name: TUBB2B |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9BVA1 |
PRO Name | tubulin beta-2B chain (human) |
Definition | A tubulin beta-2B chain that is encoded in the genome of human. |
Short Label | hTUBB2B |
Category | organism-gene |
Q9BVA1 (TUBB2B) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
R2 | Methylation | score1 | PhosphoSitePlus | |||
K19 | Acetylation | score1 | PhosphoSitePlus | |||
K19 | Methylation | score1 | PhosphoSitePlus | |||
T33 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18452278 | ||
S35 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18452278 | ||
Y36 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y50 | Phosphorylation | score1 | PhosphoSitePlus | |||
K58 | Acetylation | score1 | PhosphoSitePlus | |||
K58 | Ubiquitination | score1 | PhosphoSitePlus | |||
T72 | Phosphorylation | score1 | PhosphoSitePlus | |||
S75 | Phosphorylation | score1 | PhosphoSitePlus | |||
S78 | Phosphorylation | score1 | PhosphoSitePlus | |||
S95 | Phosphorylation | score1 | PhosphoSitePlus | |||
K103 | Acetylation | score1 | PhosphoSitePlus | |||
K103 | Sumoylation | score1 | PhosphoSitePlus | |||
K103 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y106 | Phosphorylation | score1 | PhosphoSitePlus | |||
T107 | Phosphorylation | score1 | PhosphoSitePlus | |||
S115 | Phosphorylation | score1 | PhosphoSitePlus | |||
K122 | Ubiquitination | score1 | PhosphoSitePlus | |||
S126 | Phosphorylation | score1 | PhosphoSitePlus | |||
K154 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y159 | Phosphorylation | score1 | PhosphoSitePlus | |||
R162 | Methylation | score1 | PhosphoSitePlus | |||
T166 | Phosphorylation | score1 | PhosphoSitePlus | |||
S168 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
S172 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 16371510 | ||
Y183 | Phosphorylation | score1 | PhosphoSitePlus | |||
T196 | Phosphorylation | score1 | PhosphoSitePlus | |||
T199 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y200 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y208 | Phosphorylation | score1 | PhosphoSitePlus | |||
K216 | Acetylation | score1 | PhosphoSitePlus | |||
K216 | Ubiquitination | score1 | PhosphoSitePlus | |||
T218 | Phosphorylation | score1 | PhosphoSitePlus | |||
T219 | Phosphorylation | score1 | PhosphoSitePlus | |||
T221 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y222 | Phosphorylation | score1 | PhosphoSitePlus | |||
S234 | Phosphorylation | score1 | PhosphoSitePlus | |||
K252 | Acetylation | score1 | PhosphoSitePlus | |||
K252 | Sumoylation | score1 | PhosphoSitePlus | |||
K252 | Ubiquitination | score1 | PhosphoSitePlus | |||
T274 | Phosphorylation | score1 | PhosphoSitePlus | |||
S275 | Phosphorylation | score1 | PhosphoSitePlus | |||
R276 | Methylation | score1 | PhosphoSitePlus | |||
S278 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y281 | Phosphorylation | score1 | PhosphoSitePlus | |||
T290 | Phosphorylation | score1 | PhosphoSitePlus | |||
K297 | Ubiquitination | score1 | PhosphoSitePlus | |||
C303 | Methylation | score1 | IEDB | 31844290 | ||
S322 | Phosphorylation | score1 | PhosphoSitePlus | |||
K324 | Acetylation | score1 | PhosphoSitePlus | |||
K324 | Sumoylation | score1 | PhosphoSitePlus | |||
K324 | Ubiquitination | score1 | PhosphoSitePlus | |||
K336 | Acetylation | score1 | PhosphoSitePlus | |||
K336 | Ubiquitination | score1 | PhosphoSitePlus | |||
S338 | Phosphorylation | score1 | PhosphoSitePlus | |||
S339 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y340 | Phosphorylation | score1 | PhosphoSitePlus | |||
K350 | Sumoylation | score1 | PhosphoSitePlus | |||
K350 | Ubiquitination | score1 | PhosphoSitePlus | |||
T351 | Phosphorylation | score1 | PhosphoSitePlus | |||
C354 | Methylation | score1 | IEDB | 31844290 | ||
K362 | Ubiquitination | score1 | PhosphoSitePlus | |||
T366 | Phosphorylation | score1 | PhosphoSitePlus | |||
K379 | Acetylation | score1 | PhosphoSitePlus | |||
K379 | Ubiquitination | score1 | PhosphoSitePlus | |||
S382 | Phosphorylation | score1 | PhosphoSitePlus | |||
T386 | Phosphorylation | score1 | PhosphoSitePlus | |||
K392 | Ubiquitination | score1 | PhosphoSitePlus | |||
T399 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R2 | H2 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K19 | M19 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
K58 | T58 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K58 | R58 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T72 | M72 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S75 | L75 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S78 | T78 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S78 | Y78 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S78 | P78 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S115 | L115 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
R162 | C162 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
T166 | S166 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S168 | N168 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] |