iPTMnet Report for Q9BVA1 (TUBB2B)
Protein Information
| UniProt AC / UniProt ID | Q9BVA1 / TBB2B_HUMAN |
| Protein Name | Tubulin beta-2B chain |
| Gene Name | Name: TUBB2B |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9BVA1 |
| PRO Name | tubulin beta-2B chain (human) |
| Definition | A tubulin beta-2B chain that is encoded in the genome of human. |
| Short Label | hTUBB2B |
| Category | organism-gene |
Q9BVA1 (TUBB2B) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| R2 | Methylation | score1 | PhosphoSitePlus | |||
| K19 | Acetylation | score1 | PhosphoSitePlus | |||
| K19 | Methylation | score1 | PhosphoSitePlus | |||
| T33 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18452278 | ||
| S35 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18452278 | ||
| Y36 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y50 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K58 | Acetylation | score1 | PhosphoSitePlus | |||
| K58 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T72 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S75 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S78 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S95 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K103 | Acetylation | score1 | PhosphoSitePlus | |||
| K103 | Sumoylation | score1 | PhosphoSitePlus | |||
| K103 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y106 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T107 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S115 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K122 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S126 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K154 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y159 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R162 | Methylation | score1 | PhosphoSitePlus | |||
| T166 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S168 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| S172 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 16371510 | ||
| Y183 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T196 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T199 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y200 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y208 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K216 | Acetylation | score1 | PhosphoSitePlus | |||
| K216 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T218 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T219 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T221 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y222 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S234 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K252 | Acetylation | score1 | PhosphoSitePlus | |||
| K252 | Sumoylation | score1 | PhosphoSitePlus | |||
| K252 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T274 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S275 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R276 | Methylation | score1 | PhosphoSitePlus | |||
| S278 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y281 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T290 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K297 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C303 | Methylation | score1 | IEDB | 31844290 | ||
| S322 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K324 | Acetylation | score1 | PhosphoSitePlus | |||
| K324 | Sumoylation | score1 | PhosphoSitePlus | |||
| K324 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K336 | Acetylation | score1 | PhosphoSitePlus | |||
| K336 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S338 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S339 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y340 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K350 | Sumoylation | score1 | PhosphoSitePlus | |||
| K350 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T351 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C354 | Methylation | score1 | IEDB | 31844290 | ||
| K362 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T366 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K379 | Acetylation | score1 | PhosphoSitePlus | |||
| K379 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S382 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T386 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K392 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T399 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R2 | H2 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K19 | M19 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| K58 | T58 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K58 | R58 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T72 | M72 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S75 | L75 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| S78 | T78 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S78 | Y78 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S78 | P78 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S115 | L115 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| R162 | C162 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| T166 | S166 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S168 | N168 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] |
DAG View