iPTMnet Report for Q9BV94 (EDEM2)
Protein Information
UniProt AC / UniProt ID | Q9BV94 / EDEM2_HUMAN |
Protein Name | ER degradation-enhancing alpha-mannosidase-like protein 2 precursor |
Gene Name | Name: EDEM2 Synonyms:C20orf31,C20orf49;ORFNames:UNQ573/PRO1135; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9BV94 |
PRO Name | ER degradation-enhancing alpha-mannosidase-like protein 2 (human) |
Definition | An ER degradation-enhancing alpha-mannosidase-like protein 2 that is encoded in the genome of human. |
Short Label | hEDEM2 |
Category | organism-gene |
Q9BV94 (EDEM2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
K275 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y283 | Phosphorylation | score1 | PhosphoSitePlus | |||
K402 | Ubiquitination | score1 | PhosphoSitePlus | |||
K405 | Ubiquitination | score1 | PhosphoSitePlus | |||
K414 | Ubiquitination | score1 | PhosphoSitePlus | |||
K492 | Ubiquitination | score1 | PhosphoSitePlus | |||
K517 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K402 | N402 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] |