Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BV73 / CP250_HUMAN
Protein Name Centrosome-associated protein CEP250
Gene Name Name: CEP250
Synonyms:CEP2,CNAP1;
Organism Homo sapiens (Human)

PRO ID PR:Q9BV73
DAG View
PRO Name centrosome-associated protein CEP250 (human)
Definition A centrosome-associated protein CEP250 that is encoded in the genome of human.
Short Label hCEP250
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BV73 (CEP250) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation PhosphoSitePlus
K12 Acetylation PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus
T54 Phosphorylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
T186 Phosphorylation PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
T253 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
T293 Phosphorylation PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus
K297 Acetylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
K463 Ubiquitination PhosphoSitePlus
K588 Ubiquitination PhosphoSitePlus
K600 Ubiquitination PhosphoSitePlus
K652 Ubiquitination PhosphoSitePlus
S699 Phosphorylation PhosphoSitePlus
T842 Phosphorylation PhosphoSitePlus
K892 Ubiquitination PhosphoSitePlus
S929 Phosphorylation PhosphoSitePlus
T933 Phosphorylation PhosphoSitePlus
K956 Ubiquitination PhosphoSitePlus
T971 Phosphorylation PhosphoSitePlus
K1010 Ubiquitination PhosphoSitePlus
K1016 Ubiquitination PhosphoSitePlus
K1036 Ubiquitination PhosphoSitePlus
T1040 Phosphorylation PhosphoSitePlus
K1048 Acetylation PhosphoSitePlus
K1048 Ubiquitination PhosphoSitePlus
K1148 Ubiquitination PhosphoSitePlus
K1254 Ubiquitination PhosphoSitePlus
K1268 Ubiquitination PhosphoSitePlus
K1280 Ubiquitination PhosphoSitePlus
S1295 Phosphorylation PhosphoSitePlus
S1310 Phosphorylation PhosphoSitePlus
S1313 Phosphorylation PhosphoSitePlus
S1324 Phosphorylation PhosphoSitePlus
S1386 Phosphorylation PhosphoSitePlus
K1412 Ubiquitination PhosphoSitePlus
K1417 Ubiquitination PhosphoSitePlus
K1449 Ubiquitination PhosphoSitePlus
K1466 Ubiquitination PhosphoSitePlus
K1484 Ubiquitination PhosphoSitePlus
K1502 Ubiquitination PhosphoSitePlus
K1533 Ubiquitination PhosphoSitePlus
K1574 Ubiquitination PhosphoSitePlus
K1577 Ubiquitination PhosphoSitePlus
S1601 Phosphorylation PhosphoSitePlus
S1609 Phosphorylation PhosphoSitePlus
S1618 Phosphorylation PhosphoSitePlus
K1664 Ubiquitination PhosphoSitePlus
K1679 Ubiquitination PhosphoSitePlus
K1689 Ubiquitination PhosphoSitePlus
T1701 Phosphorylation PhosphoSitePlus
S1723 Phosphorylation PhosphoSitePlus
K1797 Ubiquitination PhosphoSitePlus
T1853 Phosphorylation PhosphoSitePlus
K1855 Ubiquitination PhosphoSitePlus
K1865 Ubiquitination PhosphoSitePlus
K1901 Ubiquitination PhosphoSitePlus
S1927 Phosphorylation PhosphoSitePlus
K1936 Ubiquitination PhosphoSitePlus
K1972 Ubiquitination PhosphoSitePlus
K1980 Ubiquitination PhosphoSitePlus
K2063 Ubiquitination PhosphoSitePlus
S2064 Phosphorylation PhosphoSitePlus   RLIMS-P 32606248
K2077 Ubiquitination PhosphoSitePlus
S2095 Phosphorylation PhosphoSitePlus
S2128 Phosphorylation PhosphoSitePlus
K2130 Ubiquitination PhosphoSitePlus
S2132 Phosphorylation PhosphoSitePlus
S2138 Phosphorylation PhosphoSitePlus   UniProt 23186163
K2140 Ubiquitination PhosphoSitePlus
S2143 Phosphorylation PhosphoSitePlus
K2172 Ubiquitination PhosphoSitePlus
S2179 Phosphorylation PhosphoSitePlus   RLIMS-P 24695856
T2218 Phosphorylation PhosphoSitePlus   UniProt 23186163
S2229 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
T2233 Phosphorylation PhosphoSitePlus
S2234 Phosphorylation PhosphoSitePlus   RLIMS-P 24695856
S2252 Phosphorylation PhosphoSitePlus   UniProt 19690332
S2259 Phosphorylation PhosphoSitePlus
K2265 Ubiquitination PhosphoSitePlus
S2267 Phosphorylation PhosphoSitePlus
S2322 Phosphorylation PhosphoSitePlus   UniProt 23186163
K2327 Ubiquitination PhosphoSitePlus
S2332 Phosphorylation PhosphoSitePlus
K2347 Ubiquitination PhosphoSitePlus
T2364 Phosphorylation PhosphoSitePlus
Y2373 Phosphorylation PhosphoSitePlus
S2390 Phosphorylation PhosphoSitePlus
S2392 Phosphorylation P51955 (NEK2) , Q9H0K1 (SIK2) PhosphoSitePlus   RLIMS-P   Signor 20708153, 24695856
S2394 Phosphorylation Q9H0K1 (SIK2) , P51955 (NEK2) PhosphoSitePlus   RLIMS-P   Signor 20708153, 24695856
S2417 Phosphorylation P51955 (NEK2) PhosphoSitePlus   RLIMS-P   UniProt 21076410, 25660448, 24695856
T2419 Phosphorylation PhosphoSitePlus
S2421 Phosphorylation P51955 (NEK2) PhosphoSitePlus   RLIMS-P   UniProt 21076410, 25660448, 24695856
S2424 Phosphorylation PhosphoSitePlus
S2433 Phosphorylation PhosphoSitePlus
T2437 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S581 Phosphorylation HPRD 20068231
S583 Phosphorylation HPRD 20068231
S1060 Phosphorylation HPRD 20068231
S1310 Phosphorylation HPRD 18452278
S1313 Phosphorylation HPRD 18452278
S1324 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K62 M62 Biomuta DOID:3571 / liver cancer [ icgc ]
K600 T600 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K652 T652 Biomuta DOID:1324 / lung cancer [ tcga ]
S1313 Y1313 Biomuta DOID:363 / uterine cancer [ tcga ]
S1324 C1324 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1324 F1324 Biomuta DOID:1909 / melanoma [ tcga ]
K1466 N1466 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K1574 N1574 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:10283 / prostate cancer [ cosmic ]
K1679 M1679 Biomuta DOID:263 / kidney cancer [ tcga ]
K2130 E2130 Biomuta DOID:1324 / lung cancer [ cosmic ]
S2143 Y2143 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
T2364 P2364 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S2421 N2421 Biomuta DOID:169 / neuroendocrine tumor [ tcga ]
S2433 R2433 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]