iPTMnet Report for Q9BV68 (RNF126)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BV68 / RN126_HUMAN
Protein Name E3 ubiquitin-protein ligase RNF126
Gene Name Name: RNF126
Organism Homo sapiens (Human)

PRO ID PR:Q9BV68
DAG View
PRO Name E3 ubiquitin-protein ligase RNF126 (human)
Definition An E3 ubiquitin-protein ligase RNF126 that is encoded in the genome of human.
Short Label hRNF126
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BV68 (RNF126) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 20068231
S5 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 23186163, 20068231
S17 Phosphorylation PhosphoSitePlus
R128 Methylation PhosphoSitePlus
R130 Methylation PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
S293 Phosphorylation PhosphoSitePlus
S294 Phosphorylation PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus
S296 Phosphorylation PhosphoSitePlus
S301 Phosphorylation HPRD 18691976


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R128 H128 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
R130 L130 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S294 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S301 L301 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T308 A308 Biomuta DOID:363 / uterine cancer [ icgc ]