iPTMnet Report for Q9BV40 (VAMP8)
Protein Information
UniProt AC / UniProt ID | Q9BV40 / VAMP8_HUMAN |
Protein Name | Vesicle-associated membrane protein 8 |
Gene Name | Name: VAMP8 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9BV40 |
PRO Name | vesicle-associated membrane protein 8 (human) |
Definition | A vesicle-associated membrane protein 8 that is encoded in the genome of human. |
Short Label | hVAMP8 |
Category | organism-gene |
Q9BV40 (VAMP8) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 19413330, 25944712 | ||
S5 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
R12 | Methylation | score1 | PhosphoSitePlus | |||
S18 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 19651622, 23186163, 20068231 | ||
K24 | Ubiquitination | score1 | PhosphoSitePlus | |||
T28 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 19651622, 23186163 | ||
K47 | Acetylation | score1 | PhosphoSitePlus | |||
K47 | Ubiquitination | score1 | PhosphoSitePlus | |||
T48 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 20166139, 23186163 | ||
T54 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 23186163, 20068231 | ||
S55 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K59 | Ubiquitination | score1 | PhosphoSitePlus | |||
K64 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R12 | C12 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K24 | T24 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S55 | F55 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |