iPTMnet Report for Q9BV36 (MLPH)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BV36 / MELPH_HUMAN
Protein Name Melanophilin
Gene Name Name: MLPH
Synonyms:SLAC2A;
Organism Homo sapiens (Human)

PRO ID PR:Q9BV36
DAG View
PRO Name melanophilin (human)
Definition A melanophilin that is encoded in the genome of human.
Short Label hMLPH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BV36 (MLPH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K136 Ubiquitination PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
T165 Phosphorylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
K185 Acetylation PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
S223 Phosphorylation PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
T228 Phosphorylation PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
S266 Phosphorylation IEDB   PhosphoSitePlus 27869121, 32157095
S295 Phosphorylation PhosphoSitePlus
T313 Phosphorylation PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
S318 Phosphorylation PhosphoSitePlus
S326 Phosphorylation PhosphoSitePlus
S336 Phosphorylation PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
S397 Phosphorylation PhosphoSitePlus
T401 Phosphorylation PhosphoSitePlus
S402 Phosphorylation PhosphoSitePlus
S403 Phosphorylation PhosphoSitePlus
S420 Phosphorylation PhosphoSitePlus
S444 Phosphorylation PhosphoSitePlus
Y454 Phosphorylation PhosphoSitePlus
T457 Phosphorylation PhosphoSitePlus
T458 Phosphorylation PhosphoSitePlus
S463 Phosphorylation PhosphoSitePlus
S481 Phosphorylation PhosphoSitePlus
S484 Phosphorylation PhosphoSitePlus
S510 Phosphorylation PhosphoSitePlus
S552 Phosphorylation PhosphoSitePlus
S554 Phosphorylation PhosphoSitePlus
K560 Ubiquitination PhosphoSitePlus
S569 Phosphorylation PhosphoSitePlus
Y571 Phosphorylation PhosphoSitePlus
S574 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S336 Phosphorylation PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
S524 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S140 F140 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S173 L173 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S231 Y231 Biomuta DOID:3565 / meningioma [ cosmic ]
S233 L233 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S397 G397 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S402 L402 Biomuta DOID:4159 / skin cancer [ cosmic ]
S402 P402 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S444 R444 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T457 A457 Biomuta DOID:184 / bone cancer [ cosmic ]
S524 T524 Biomuta DOID:4159 / skin cancer [ cosmic ]
S552 T552 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y571 C571 Biomuta DOID:9256 / colorectal cancer [ cosmic ]