iPTMnet Report for Q9BUZ4 (TRAF4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BUZ4 / TRAF4_HUMAN
Protein Name TNF receptor-associated factor 4
Gene Name Name: TRAF4
Synonyms:CART1,MLN62,RNF83;
Organism Homo sapiens (Human)

PRO ID PR:Q9BUZ4
DAG View
PRO Name TNF receptor-associated factor 4 (human)
Definition A TNF receptor-associated factor 4 that is encoded in the genome of human.
Short Label hTRAF4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BUZ4 (TRAF4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y6 Phosphorylation PhosphoSitePlus
K7 Ubiquitination PhosphoSitePlus
K11 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
Y166 Phosphorylation PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
Y212 Phosphorylation PhosphoSitePlus
S242 Phosphorylation PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
K327 Ubiquitination PhosphoSitePlus
K415 Ubiquitination PhosphoSitePlus
K419 Ubiquitination PhosphoSitePlus
T422 Phosphorylation PhosphoSitePlus
S426 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 18669648, 23186163, 22547678, ...20068231
S426 Phosphorylation O15111 (CHUK) neXtProt   PhosphoSitePlus   Signor 22547678
S430 Phosphorylation PhosphoSitePlus
K438 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T422 Phosphorylation HPRD 20068231
S426 Phosphorylation HPRD 18669648, 19664994, 19664995, ...20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y166 * Biomuta DOID:263 / kidney cancer [ cosmic ]
K327 E327 Biomuta DOID:9256 / colorectal cancer [ cosmic ]