iPTMnet Report for Q9BUQ8 (DDX23)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BUQ8 / DDX23_HUMAN
Protein Name Probable ATP-dependent RNA helicase DDX23
Gene Name Name: DDX23
Organism Homo sapiens (Human)

PRO ID PR:Q9BUQ8
DAG View
PRO Name probable ATP-dependent RNA helicase DDX23 (human)
Definition A probable ATP-dependent RNA helicase DDX23 that is encoded in the genome of human.
Short Label hDDX23
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BUQ8 (DDX23) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S14 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 16083285, 17081983, ...20068231
S16 Phosphorylation PhosphoSitePlus   UniProt 20068231
S23 Phosphorylation PhosphoSitePlus
T25 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S67 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S106 Phosphorylation PhosphoSitePlus
S107 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983
S109 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983
S124 Phosphorylation PhosphoSitePlus
K136 Acetylation PhosphoSitePlus
K138 Acetylation PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
K150 Acetylation PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
K251 Ubiquitination PhosphoSitePlus
R253 Methylation PhosphoSitePlus
T264 Phosphorylation PhosphoSitePlus
R301 Methylation PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
Y377 Phosphorylation PhosphoSitePlus
S378 Phosphorylation PhosphoSitePlus
T380 Phosphorylation PhosphoSitePlus
T381 Phosphorylation PhosphoSitePlus
T437 Phosphorylation PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus
Y470 Phosphorylation PhosphoSitePlus
T477 Phosphorylation PhosphoSitePlus
R508 Methylation PhosphoSitePlus
T579 Phosphorylation PhosphoSitePlus
T602 Phosphorylation PhosphoSitePlus
Y620 Phosphorylation PhosphoSitePlus
Y628 Phosphorylation PhosphoSitePlus
K642 Acetylation PhosphoSitePlus
S647 Phosphorylation PhosphoSitePlus
K686 Ubiquitination PhosphoSitePlus
K698 Ubiquitination PhosphoSitePlus
K711 Ubiquitination PhosphoSitePlus
K715 Acetylation PhosphoSitePlus
Y748 Phosphorylation PhosphoSitePlus
T755 Phosphorylation PhosphoSitePlus
S761 Phosphorylation PhosphoSitePlus
Y777 Phosphorylation PhosphoSitePlus
S790 Phosphorylation PhosphoSitePlus
T807 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S14 Phosphorylation HPRD 19651622, 19007248, 20068231
S16 Phosphorylation HPRD 20068231
S23 Phosphorylation HPRD 20068231
T25 Phosphorylation HPRD 20068231
S106 Phosphorylation HPRD 20068231
S107 Phosphorylation HPRD 19651622, 17081983, 20068231
S109 Phosphorylation HPRD 19651622, 17081983, 20068231
S124 Phosphorylation HPRD 20068231
T602 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S23 L23 Biomuta DOID:263 / kidney cancer [ cosmic ]
S67 T67 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S109 F109 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S143 F143 Biomuta DOID:4159 / skin cancer [ cosmic ]
K251 R251 Biomuta DOID:263 / kidney cancer [ cosmic ]
T264 M264 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic ]
K326 E326 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S378 C378 Biomuta DOID:1324 / lung cancer [ cosmic ]
T437 I437 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y470 N470 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y620 C620 Biomuta DOID:3571 / liver cancer [ cosmic ]
S647 P647 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]