Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BUJ2 / HNRL1_HUMAN
Protein Name Heterogeneous nuclear ribonucleoprotein U-like protein 1
Gene Name Name: HNRNPUL1
Synonyms:E1BAP5,HNRPUL1;
Organism Homo sapiens (Human)

PRO ID PR:Q9BUJ2
DAG View
PRO Name heterogeneous nuclear ribonucleoprotein U-like protein 1 (human)
Definition A heterogeneous nuclear ribonucleoprotein U-like protein 1 that is encoded in the genome of human.
Short Label hHNRNPUL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BUJ2 (HNRNPUL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T22 O-Glycosylation GlyGen 27655845, 30397120, 29351928, ...32119511, 28510447, 22121020, 29237092
R23 Methylation PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
Y111 Phosphorylation PhosphoSitePlus
K117 Sumoylation PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
Y124 Phosphorylation PhosphoSitePlus
Y137 Phosphorylation PhosphoSitePlus
K142 Sumoylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K146 Sumoylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
T151 Phosphorylation PhosphoSitePlus
S152 Phosphorylation PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
K162 Acetylation PhosphoSitePlus
K162 Sumoylation PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
K172 Methylation PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
R173 Methylation PhosphoSitePlus
Y175 Phosphorylation PhosphoSitePlus
R179 Methylation PhosphoSitePlus
R181 Methylation PhosphoSitePlus
Y183 Phosphorylation PhosphoSitePlus
S194 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 18220336, 18669648, ...24275569, 17693683, 19690332
T209 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T215 Phosphorylation PhosphoSitePlus
K270 Acetylation PhosphoSitePlus
K270 Ubiquitination PhosphoSitePlus
K309 Ubiquitination PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
C377 S-Nitrosylation dbSNO 22178444, 19366988, 18335467
K418 Ubiquitination PhosphoSitePlus
K440 Acetylation PhosphoSitePlus
K440 Methylation PhosphoSitePlus
K440 Sumoylation PhosphoSitePlus
K440 Ubiquitination PhosphoSitePlus
S444 Phosphorylation PhosphoSitePlus
K448 Sumoylation PhosphoSitePlus
K449 Sumoylation PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
Y450 Phosphorylation PhosphoSitePlus
T455 Phosphorylation PhosphoSitePlus
K461 Ubiquitination PhosphoSitePlus
C487 S-Nitrosylation dbSNO 22178444, 19366988, 18335467
Y510 Phosphorylation PhosphoSitePlus
S512 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 15302935, ...19690332, 20068231
K517 Ubiquitination PhosphoSitePlus
K527 Sumoylation PhosphoSitePlus
K527 Ubiquitination PhosphoSitePlus
C532 S-Nitrosylation dbSNO 26338901
K539 Sumoylation PhosphoSitePlus
K539 Ubiquitination PhosphoSitePlus
K562 Sumoylation PhosphoSitePlus
R584 Methylation PhosphoSitePlus
R592 Methylation PhosphoSitePlus
K600 Sumoylation PhosphoSitePlus
K600 Ubiquitination PhosphoSitePlus
R612 Methylation PhosphoSitePlus
R618 Methylation PhosphoSitePlus
R620 Methylation PhosphoSitePlus
R628 Methylation PhosphoSitePlus
R632 Methylation PhosphoSitePlus
R639 Methylation PhosphoSitePlus   UniProt 24129315
R645 Methylation PhosphoSitePlus   UniProt 24129315
S649 Phosphorylation PhosphoSitePlus
R656 Methylation PhosphoSitePlus   UniProt 24129315
R661 Methylation PhosphoSitePlus
S668 Phosphorylation PhosphoSitePlus
R671 Methylation PhosphoSitePlus   UniProt 24129315
R685 Methylation PhosphoSitePlus
S687 Phosphorylation PhosphoSitePlus
R690 Methylation PhosphoSitePlus
S716 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus 18669648, 18847512
Y717 Phosphorylation PhosphoSitePlus
S718 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   UniProt 18669648, 15302935, 18847512
S733 O-Glycosylation GlyGen 27655845, 30397120, 29351928, ...32119511, 28510447, 22121020, 29237092
S738 O-Glycosylation GlyGen 27655845, 30397120, 29351928, ...32119511, 28510447, 22121020, 29237092
S739 O-Glycosylation GlyGen 27655845, 30397120, 29351928, ...32119511, 28510447, 22121020, 29237092
T742 O-Glycosylation GlyGen 27655845, 30397120, 29351928, ...32119511, 28510447, 22121020, 29237092
S743 O-Glycosylation GlyGen 27655845, 30397120, 29351928, ...32119511, 28510447, 22121020, 29237092
T744 O-Glycosylation GlyGen 27655845, 30397120, 29351928, ...32119511, 28510447, 22121020, 29237092
T746 O-Glycosylation GlyGen 27655845, 30397120, 29351928, ...32119511, 28510447, 22121020, 29237092
S748 O-Glycosylation GlyGen 27655845, 30397120, 29351928, ...32119511, 28510447, 22121020, 29237092
S749 O-Glycosylation GlyGen 27655845, 30397120, 29351928, ...32119511, 28510447, 22121020, 29237092
T798 O-Glycosylation GlyGen 27655845, 30397120, 29351928, ...32119511, 28510447, 22121020, 29237092
T804 O-Glycosylation GlyGen 27655845, 30397120, 29351928, ...32119511, 28510447, 22121020, 29237092
Site PTM Type PTM Enzyme Score Source PMID
S194 Phosphorylation HPRD 20058876, 18452278, 18669648, ...16055720, 17693683, 20068231
T209 Phosphorylation HPRD 18669648
S512 Phosphorylation HPRD 15302935, 19664994, 20068231
S649 Phosphorylation HPRD 20068231
S716 Phosphorylation HPRD 19413330, 18669648, 20068231, ...20230923
Y717 Phosphorylation HPRD 19664995
S718 Phosphorylation HPRD 19413330, 18669648, 19664995, ...15144186, 20230923
Site PTM Type PTM Enzyme Score Source PMID
S94 Phosphorylation HPRD 20058876, 18452278, 18669648, ...16055720, 17693683, 20068231
T109 Phosphorylation HPRD 18669648
S412 Phosphorylation HPRD 15302935, 19664994, 20068231
S549 Phosphorylation HPRD 20068231
S616 Phosphorylation HPRD 19413330, 18669648, 20068231, ...20230923
Y617 Phosphorylation HPRD 19664995
S618 Phosphorylation HPRD 19413330, 18669648, 19664995, ...15144186, 20230923


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y111 * Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
Y111 D111 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
Y137 C137 Biomuta DOID:3571 / liver cancer [ icgc ]
T151 N151 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
K172 N172 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]
R179 P179 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
Y183 * Biomuta DOID:9256 / colorectal cancer [ icgc ]
K310 N310 Biomuta DOID:3571 / liver cancer [ icgc ]
C377 R377 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
C532 F532 Biomuta DOID:3571 / liver cancer [ icgc ]
R612 * Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
R620 H620 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
R628 H628 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
R632 Q632 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
R645 Q645 Biomuta DOID:3571 / liver cancer [ tcga ]
R656 L656 Biomuta DOID:2531 / hematologic cancer [ icgc ]
R656 * Biomuta DOID:363 / uterine cancer [ tcga ] DOID:10534 / stomach cancer [ tcga ]
R661 H661 Biomuta DOID:263 / kidney cancer [ cosmic, tcga ]
R685 S685 Biomuta DOID:11934 / head and neck cancer [ icgc, tcga ]
R685 K685 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
S687 I687 Biomuta DOID:3571 / liver cancer [ icgc ]
T744 P744 Biomuta DOID:1612 / breast cancer [ icgc ]
T746 P746 Biomuta DOID:1612 / breast cancer [ icgc ]