iPTMnet Report for Q9BUI4 (POLR3C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BUI4 / RPC3_HUMAN
Protein Name DNA-directed RNA polymerase III subunit RPC3
Gene Name Name: POLR3C
Organism Homo sapiens (Human)

PRO ID PR:Q9BUI4
DAG View
PRO Name DNA-directed RNA polymerase III subunit RPC3 (human)
Definition A DNA-directed RNA polymerase III subunit RPC3 that is encoded in the genome of human.
Short Label hPOLR3C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BUI4 (POLR3C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S33 Phosphorylation PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
C79 S-Nitrosylation dbSNO 26338901
K115 Ubiquitination PhosphoSitePlus
T138 Phosphorylation PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
T147 Phosphorylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
S194 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
K198 Ubiquitination PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
S296 Phosphorylation PhosphoSitePlus
Y301 Phosphorylation PhosphoSitePlus
S329 Phosphorylation PhosphoSitePlus
Y334 Phosphorylation PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus
C362 Methylation IEDB 31844290
K378 Ubiquitination PhosphoSitePlus
K389 Acetylation PhosphoSitePlus
K411 Ubiquitination PhosphoSitePlus
T412 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
K441 Ubiquitination PhosphoSitePlus
K463 Ubiquitination PhosphoSitePlus
T501 Phosphorylation PhosphoSitePlus
K503 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C79 Y79 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K115 N115 Biomuta DOID:1324 / lung cancer [ cosmic ]
S194 T194 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S204 L204 Biomuta [ cosmic ]