iPTMnet Report for Q9BUH6 (PAXX)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BUH6 / PAXX_HUMAN
Protein Name Protein PAXX
Gene Name Name: PAXX
Synonyms:C9orf142;
Organism Homo sapiens (Human)

PRO ID PR:Q9BUH6
DAG View
PRO Name protein PAXX (human)
Definition A protein PAXX that is encoded in the genome of human.
Short Label hPAXX
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BUH6 (PAXX) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S5 O-Glycosylation GlyGen 23301498, 35132862, 28510447, ...29351928
S5 Phosphorylation PhosphoSitePlus
T10 Phosphorylation PhosphoSitePlus
S95 Phosphorylation PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus   UniProt 27705800
T145 Phosphorylation PhosphoSitePlus   UniProt 27705800
S148 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...16964243, 27705800, 18669648, 20068231, 17081983
S152 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...27705800, 18669648, 24275569
R169 Methylation PhosphoSitePlus
C180 S-Nitrosylation dbSNO 22178444
K191 Acetylation PhosphoSitePlus
S192 O-Glycosylation GlyGen 23301498, 35132862, 28510447, ...29351928
S192 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T73 Phosphorylation HPRD 20068231
S148 Phosphorylation HPRD 19413330, 18691976, 17081983, ...16964243, 20058876, 19664994, 19664995, 19651622, 18669648, 18707149, 20166139, 19415658, 20068231, 18212344
S152 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
S192 Phosphorylation HPRD 18691976, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T10 M10 Biomuta DOID:11934 / head and neck cancer [ icgc ]
S99 L99 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S103 L103 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K191 N191 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]