Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BUF5 / TBB6_HUMAN
Protein Name Tubulin beta-6 chain
Gene Name Name: TUBB6
Organism Homo sapiens (Human)

PRO ID PR:Q9BUF5
DAG View
PRO Name tubulin beta-6 chain (human)
Definition A tubulin beta-6 chain that is encoded in the genome of human.
Short Label hTUBB6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BUF5 (TUBB6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y36 Phosphorylation HPRD   PhosphoSitePlus 18452278
S40 Phosphorylation HPRD   PhosphoSitePlus 18452278
Y50 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus
S56 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332
K58 Ubiquitination PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
T166 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
S172 Phosphorylation PhosphoSitePlus   UniProt 16371510
Y183 Phosphorylation PhosphoSitePlus
T196 Phosphorylation PhosphoSitePlus
T199 Phosphorylation PhosphoSitePlus
Y200 Phosphorylation PhosphoSitePlus
Y208 Phosphorylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
T219 Phosphorylation PhosphoSitePlus
Y222 Phosphorylation PhosphoSitePlus
S230 Phosphorylation HPRD 18691976
K252 Acetylation PhosphoSitePlus
K252 Sumoylation PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
T274 Phosphorylation PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus
R276 Methylation PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus
Y281 Phosphorylation PhosphoSitePlus
Y310 Phosphorylation PhosphoSitePlus
T315 Phosphorylation PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
S338 Phosphorylation PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
Y340 Phosphorylation PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus
K379 Acetylation PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y36 H36 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
Y50 H50 Biomuta DOID:363 / uterine cancer [ tcga ]
S55 L55 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
S55 * Biomuta DOID:5041 / esophageal cancer [ icgc ]
K58 R58 Biomuta DOID:0070003 / blastoma [ cosmic ]
K58 N58 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S172 L172 Biomuta DOID:11934 / head and neck cancer [ tcga ]
Y183 H183 Biomuta DOID:10534 / stomach cancer [ tcga ]
Y208 H208 Biomuta DOID:263 / kidney cancer [ cosmic, tcga ]
S230 F230 Biomuta DOID:1909 / melanoma [ tcga ]
S278 R278 Biomuta DOID:1324 / lung cancer [ tcga ]
Y281 H281 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]