iPTMnet Report for Q9BU64 (CENPO)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BU64 / CENPO_HUMAN
Protein Name Centromere protein O
Gene Name Name: CENPO
Synonyms:ICEN36,MCM21R;
Organism Homo sapiens (Human)

PRO ID PR:Q9BU64
DAG View
PRO Name centromere protein O (human)
Definition A centromere protein O that is encoded in the genome of human.
Short Label hCENPO
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BU64 (CENPO) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T26 Phosphorylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus   UniProt 23186163
S40 Phosphorylation PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus
T85 Phosphorylation PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus
Y183 Phosphorylation PhosphoSitePlus
S297 Phosphorylation PhosphoSitePlus
S300 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S263 Phosphorylation HPRD 19007248


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S35 F35 Biomuta DOID:4159 / skin cancer [ cosmic ]
K51 M51 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S72 I72 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
Y183 H183 Biomuta DOID:4159 / skin cancer [ cosmic ]
S263 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S297 R297 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]