iPTMnet Report for Q9BTZ2 (DHRS4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BTZ2 / DHRS4_HUMAN
Protein Name Dehydrogenase/reductase SDR family member 4
Gene Name Name: DHRS4
Synonyms:SDR25C2;ORFNames:UNQ851/PRO1800;
Organism Homo sapiens (Human)

PRO ID PR:Q9BTZ2
DAG View
PRO Name dehydrogenase/reductase SDR family member 4 (human)
Definition A dehydrogenase/reductase SDR family member 4 that is encoded in the genome of human.
Short Label hDHRS4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BTZ2 (DHRS4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S63 Phosphorylation PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
I140 Phosphorylation UniProt 18669648
T149 Phosphorylation PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
T274 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T149 Phosphorylation HPRD 19413330
Site PTM Type PTM Enzyme Score Source PMID
S129 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K194 N194 Biomuta DOID:1540 / parathyroid carcinoma [ cosmic ]
K216 T216 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K216 N216 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
T274 P274 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ]