iPTMnet Report for Q9BTV6 (DPH7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BTV6 / DPH7_HUMAN
Protein Name Diphthine methyltransferase
Gene Name Name: DPH7
Synonyms:C9orf112,WDR85;
Organism Homo sapiens (Human)

PRO ID PR:Q9BTV6
DAG View
PRO Name diphthine methyltransferase (human)
Definition A diphthine methyltransferase that is encoded in the genome of human.
Short Label hDPH7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BTV6 (DPH7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K57 Ubiquitination PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
K314 Ubiquitination PhosphoSitePlus
S341 Phosphorylation PhosphoSitePlus
S347 Phosphorylation PhosphoSitePlus
S353 Phosphorylation PhosphoSitePlus   UniProt 23186163
K363 Ubiquitination PhosphoSitePlus
K405 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K314 M314 Biomuta DOID:1324 / lung cancer [ cosmic ]
K314 N314 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S341 F341 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S353 L353 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]