iPTMnet Report for Q9BTV4 (TMEM43)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BTV4 / TMM43_HUMAN
Protein Name Transmembrane protein 43
Gene Name Name: TMEM43
ORFNames:UNQ2564/PRO6244;
Organism Homo sapiens (Human)

PRO ID PR:Q9BTV4
DAG View
PRO Name transmembrane protein 43 (human)
Definition A transmembrane protein 43 that is encoded in the genome of human.
Short Label hTMEM43
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BTV4 (TMEM43) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 25732826
N4 N-Glycosylation GlyGen 24190977
S20 Phosphorylation PhosphoSitePlus
T60 Phosphorylation PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
R131 Methylation PhosphoSitePlus
K159 Ubiquitination PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus
K199 Acetylation PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K204 Ubiquitination PhosphoSitePlus
S209 Phosphorylation HPRD   PhosphoSitePlus 20068231
K210 Ubiquitination PhosphoSitePlus
K232 Ubiquitination PhosphoSitePlus
Y233 Phosphorylation PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
S249 Phosphorylation PhosphoSitePlus
R268 Methylation PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
T282 Phosphorylation PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N4 I4 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T60 M60 Biomuta DOID:4362 / cervical cancer [ icgc ]
S102 C102 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y233 C233 Biomuta DOID:1324 / lung cancer [ cosmic ]
S244 F244 Biomuta DOID:4159 / skin cancer [ cosmic ]
K278 T278 Biomuta DOID:10534 / stomach cancer [ cosmic ]