Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BTL4 / IER2_HUMAN
Protein Name Immediate early response gene 2 protein
Gene Name Name: IER2
Synonyms:ETR101;
Organism Homo sapiens (Human)

PRO ID PR:Q9BTL4
DAG View
PRO Name immediate early response gene 2 protein (human)
Definition An immediate early response gene 2 protein that is encoded in the genome of human.
Short Label hIER2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BTL4 (IER2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
K5 Ubiquitination PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
S125 Phosphorylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus
K203 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K51 N51 Biomuta DOID:3571 / liver cancer [ icgc ]
S124 I124 Biomuta DOID:363 / uterine cancer [ tcga ]
K146 N146 Biomuta DOID:363 / uterine cancer [ tcga ]