iPTMnet Report for Q9BSW2 (CRACR2A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BSW2 / EFC4B_HUMAN
Protein Name EF-hand calcium-binding domain-containing protein 4B
Gene Name Name: CRACR2A
Synonyms:EFCAB4B,RAB46;
Organism Homo sapiens (Human)

PRO ID PR:Q9BSW2
DAG View
PRO Name EF-hand calcium-binding domain-containing protein 4B (human)
Definition An EF-hand calcium-binding domain-containing protein 4B that is encoded in the genome of human.
Short Label hCRACR2A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BSW2 (CRACR2A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S19 Phosphorylation PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
Y141 Phosphorylation PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
Y237 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
T292 Phosphorylation PhosphoSitePlus
T301 Phosphorylation PhosphoSitePlus
K309 Ubiquitination PhosphoSitePlus
T311 Phosphorylation IEDB   PhosphoSitePlus 35494241
K342 Ubiquitination PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
S410 Phosphorylation PhosphoSitePlus
K414 Ubiquitination PhosphoSitePlus
Y415 Phosphorylation PhosphoSitePlus
S424 Phosphorylation PhosphoSitePlus
S426 Phosphorylation PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus
S440 Phosphorylation PhosphoSitePlus
Y446 Phosphorylation PhosphoSitePlus
S473 Phosphorylation PhosphoSitePlus
S501 Phosphorylation PhosphoSitePlus
S521 Phosphorylation PhosphoSitePlus
K529 Ubiquitination PhosphoSitePlus
S571 Phosphorylation PhosphoSitePlus
T601 Phosphorylation PhosphoSitePlus
Y607 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K54 N54 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y141 H141 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
Y141 F141 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S143 P143 Biomuta DOID:1319 / brain cancer [ cosmic ]
K171 R171 Biomuta DOID:184 / bone cancer [ cosmic ]
T301 N301 Biomuta DOID:3571 / liver cancer [ cosmic ]
S473 F473 Biomuta DOID:363 / uterine cancer [ icgc ]
S521 P521 Biomuta DOID:9256 / colorectal cancer [ cosmic ]