Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9BST9 / RTKN_HUMAN
Protein Name Rhotekin
Gene Name Name: RTKN
Organism Homo sapiens (Human)

DAG View
PRO Name rhotekin (human)
Definition A rhotekin that is encoded in the genome of human.
Short Label hRTKN
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9BST9 (RTKN) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
R9 Methylation PhosphoSitePlus
T11 Phosphorylation PhosphoSitePlus
R14 Methylation PhosphoSitePlus   UniProt 24129315
S30 Phosphorylation PhosphoSitePlus   UniProt 24275569
S33 Phosphorylation PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus   UniProt 24275569
S108 Phosphorylation PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
K216 Acetylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
S218 Phosphorylation PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus
S220 Phosphorylation PhosphoSitePlus
S232 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S235 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S239 Phosphorylation PhosphoSitePlus
S241 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S242 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T433 Phosphorylation PhosphoSitePlus
S448 Phosphorylation Q9BZL6 (PRKD2) , O94806 (PRKD3) , Q15139 (PRKD1) neXtProt   PhosphoSitePlus 22228765
Y450 Phosphorylation PhosphoSitePlus
T465 Phosphorylation PhosphoSitePlus
T518 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S520 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
S529 Phosphorylation PhosphoSitePlus   UniProt 23186163
R531 Methylation PhosphoSitePlus
R533 Methylation PhosphoSitePlus
S543 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
R547 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S106 Phosphorylation HPRD 20166139
S220 Phosphorylation HPRD 20068231
S232 Phosphorylation HPRD 18669648, 20068231
S235 Phosphorylation HPRD 18669648
S239 Phosphorylation HPRD 20068231
S241 Phosphorylation HPRD 18669648
S242 Phosphorylation HPRD 18669648, 20068231
S543 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S93 Phosphorylation HPRD 20166139
S207 Phosphorylation HPRD 20068231
S219 Phosphorylation HPRD 18669648, 20068231
S222 Phosphorylation HPRD 18669648
S226 Phosphorylation HPRD 20068231
S228 Phosphorylation HPRD 18669648
S229 Phosphorylation HPRD 18669648, 20068231
S435 Phosphorylation Q15139 (PRKD1) PhosphoSitePlus 22228765
S507 Phosphorylation PhosphoSitePlus
S530 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S56 Phosphorylation HPRD 20166139
S170 Phosphorylation HPRD 20068231
S182 Phosphorylation HPRD 18669648, 20068231
S185 Phosphorylation HPRD 18669648
S189 Phosphorylation HPRD 20068231
S191 Phosphorylation HPRD 18669648
S192 Phosphorylation HPRD 18669648, 20068231
S493 Phosphorylation HPRD 18669648

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S30 N30 Biomuta DOID:363 / uterine cancer [ tcga ]
S115 P115 Biomuta DOID:3963 / thyroid carcinoma [ cosmic ] DOID:3070 / malignant glioma [ tcga ]
S232 L232 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S241 N241 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
T433 N433 Biomuta DOID:363 / uterine cancer [ tcga ]
T518 A518 Biomuta DOID:11934 / head and neck cancer [ tcga ]
R533 H533 Biomuta DOID:1909 / melanoma [ cosmic ]
S543 T543 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]