iPTMnet Report Q9BRY0 SLC39A3

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q9BRY0 / S39A3_HUMAN
Protein Name	Zinc transporter ZIP3
Gene Name	Name: SLC39A3 Synonyms:ZIP3;
Organism	Homo sapiens (Human)

PRO ID	PR:Q9BRY0 DAG View
PRO Name	zinc transporter ZIP3 (human)
Definition	A zinc transporter ZIP3 that is encoded in the genome of human.
Short Label	hSLC39A3
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q9BRY0 (SLC39A3) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	K36	Ubiquitination		score1	PhosphoSitePlus
	S125	Phosphorylation		score2	PhosphoSitePlus UniProt	18691976, 18669648
	S129	Phosphorylation		score1	PhosphoSitePlus
	Y147	Phosphorylation		score1	PhosphoSitePlus
	S156	Phosphorylation		score1	PhosphoSitePlus
	S163	Phosphorylation		score1	PhosphoSitePlus
	R164	Methylation		score1	PhosphoSitePlus
	S222	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T120	Phosphorylation		score0	HPRD	17081983
	S125	Phosphorylation		score0	HPRD	19651622, 18691976, 18669648, ...20068231
	S129	Phosphorylation		score0	HPRD	19651622, 18691976, 18669648, ...20068231
	S131	Phosphorylation		score0	HPRD	17081983
	Y133	Phosphorylation		score0	HPRD	17081983

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S98	Phosphorylation		score1	PhosphoSitePlus
	S99	Phosphorylation		score1	PhosphoSitePlus

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
T120	I120	Biomuta		DOID:1793 / pancreatic cancer [ cosmic ]
S125	L125	Biomuta		DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S129	N129	Biomuta		DOID:363 / uterine cancer [ cosmic, icgc ]
S131	L131	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]
Y147	C147	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]
S163	L163	Biomuta		DOID:4159 / skin cancer [ cosmic, icgc ]
R164	H164	Biomuta		DOID:3571 / liver cancer [ cosmic ]