iPTMnet Report for Q9BRQ5 (ORAI3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BRQ5 / ORAI3_HUMAN
Protein Name Protein orai-3
Gene Name Name: ORAI3
Synonyms:TMEM142C;
Organism Homo sapiens (Human)

PRO ID PR:Q9BRQ5
DAG View
PRO Name protein orai-3 (human)
Definition A protein orai-3 that is encoded in the genome of human.
Short Label hORAI3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BRQ5 (ORAI3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K2 Ubiquitination PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus
T190 Phosphorylation PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
S205 O-Glycosylation GlyGen 30459171
S213 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S214 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S216 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
S220 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
K274 Ubiquitination PhosphoSitePlus
Y278 Phosphorylation HPRD   PhosphoSitePlus 18491316
K279 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T190 I190 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S214 F214 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S216 F216 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S220 P220 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S220 F220 Biomuta [ cosmic ]
Y278 F278 Biomuta DOID:3571 / liver cancer [ cosmic ]