iPTMnet Report for Q9BRP8 (PYM1)
Protein Information
UniProt AC / UniProt ID | Q9BRP8 / PYM1_HUMAN |
Protein Name | Partner of Y14 and mago |
Gene Name | Name: PYM1 Synonyms:PYM,WIBG; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9BRP8 |
PRO Name | partner of Y14 and mago (human) |
Definition | A protein wibg that is encoded in the genome of human. |
Short Label | hPYM1 |
Category | organism-gene |
Q9BRP8 (PYM1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 19413330, 20068231 | ||
S6 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 20068231 | ||
Y15 | Phosphorylation | score1 | PhosphoSitePlus | |||
T25 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y36 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y45 | Phosphorylation | score1 | PhosphoSitePlus | |||
K48 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y49 | Phosphorylation | score1 | PhosphoSitePlus | |||
K51 | Ubiquitination | score1 | PhosphoSitePlus | |||
S64 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
T68 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
T72 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 17287340 | ||
K103 | Acetylation | score1 | PhosphoSitePlus | |||
T112 | Phosphorylation | score1 | PhosphoSitePlus | |||
S117 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S139 | Phosphorylation | score1 | PhosphoSitePlus | |||
S144 | Phosphorylation | score1 | PhosphoSitePlus | |||
S177 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y49 | C49 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K51 | T51 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S117 | F117 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S139 | F139 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
S144 | * | Biomuta | DOID:4362 / cervical cancer [ cosmic ] |