iPTMnet Report for Q9BRP4 (PAAF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BRP4 / PAAF1_HUMAN
Protein Name Proteasomal ATPase-associated factor 1
Gene Name Name: PAAF1
Synonyms:WDR71;
Organism Homo sapiens (Human)

PRO ID PR:Q9BRP4
DAG View
PRO Name proteasomal ATPase-associated factor 1 (human)
Definition A proteasomal ATPase-associated factor 1 that is encoded in the genome of human.
Short Label hPAAF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BRP4 (PAAF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
K65 Ubiquitination PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
R103 Methylation PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
T182 Phosphorylation PhosphoSitePlus
R187 Methylation PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus
S195 Phosphorylation PhosphoSitePlus
T199 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
C265 Methylation IEDB 31844290
K373 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R103 K103 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R103 T103 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
R187 Q187 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
C265 Y265 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
C265 G265 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K373 Q373 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]