iPTMnet Report for Q9BQS8 (FYCO1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BQS8 / FYCO1_HUMAN
Protein Name FYVE and coiled-coil domain-containing protein 1
Gene Name Name: FYCO1
Synonyms:ZFYVE7;
Organism Homo sapiens (Human)

PRO ID PR:Q9BQS8
DAG View
PRO Name FYVE and coiled-coil domain-containing protein 1 (human)
Definition A FYVE and coiled-coil domain-containing protein 1 that is encoded in the genome of human.
Short Label hFYCO1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BQS8 (FYCO1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
T22 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus   UniProt 23186163
S268 Phosphorylation PhosphoSitePlus
T276 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus   UniProt 24275569
S367 Phosphorylation PhosphoSitePlus
K416 Ubiquitination PhosphoSitePlus
S547 Phosphorylation PhosphoSitePlus
T603 Phosphorylation PhosphoSitePlus
S609 Phosphorylation PhosphoSitePlus
K623 Ubiquitination PhosphoSitePlus
S662 Phosphorylation PhosphoSitePlus
S735 Phosphorylation PhosphoSitePlus
S849 Phosphorylation PhosphoSitePlus
S878 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332
C882 S-Nitrosylation dbSNO 26338901
Y1136 Phosphorylation PhosphoSitePlus
S1155 Phosphorylation PhosphoSitePlus
S1343 Phosphorylation PhosphoSitePlus
S1427 Phosphorylation PhosphoSitePlus
Y1472 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S878 Phosphorylation HPRD 17525332, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 P2 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K44 T44 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K416 E416 Biomuta DOID:363 / uterine cancer [ icgc ]
T603 N603 Biomuta DOID:3571 / liver cancer [ cosmic ]
S609 N609 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S849 L849 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1155 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]