Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9BQL6 / FERM1_HUMAN
Protein Name Fermitin family homolog 1
Gene Name Name: FERMT1
Organism Homo sapiens (Human)

DAG View
PRO Name fermitin family homolog 1 (human)
Definition A fermitin family homolog 1 that is encoded in the genome of human.
Short Label hFERMT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9BQL6 (FERMT1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K148 Acetylation PhosphoSitePlus
S169 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S170 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T172 Phosphorylation phospho.ELM 18669648
S174 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S176 Phosphorylation PhosphoSitePlus
S179 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Y191 Phosphorylation PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus   UniProt 23186163
K371 Ubiquitination PhosphoSitePlus
Y392 Phosphorylation PhosphoSitePlus
K435 Acetylation PhosphoSitePlus
Y452 Phosphorylation PhosphoSitePlus
S502 Phosphorylation phospho.ELM 18669648
S506 Phosphorylation PhosphoSitePlus
S520 Phosphorylation PhosphoSitePlus
K592 Ubiquitination PhosphoSitePlus
T663 Phosphorylation PhosphoSitePlus
K671 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S169 Phosphorylation HPRD 18669648, 20068231
S170 Phosphorylation HPRD 18669648, 20068231
T172 Phosphorylation HPRD 18669648
S174 Phosphorylation HPRD 18669648
S179 Phosphorylation HPRD 18669648, 20068231
S502 Phosphorylation HPRD 18669648

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K148 N148 Biomuta DOID:1324 / lung cancer [ tcga ]
S169 C169 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S170 Y170 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
S502 Y502 Biomuta DOID:3571 / liver cancer [ icgc ]
S520 L520 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
K671 R671 Biomuta DOID:9256 / colorectal cancer [ tcga ]