iPTMnet Report for Q9BQL6 (FERMT1)
Protein Information
| UniProt AC / UniProt ID | Q9BQL6 / FERM1_HUMAN |
| Protein Name | Fermitin family homolog 1 |
| Gene Name | Name: FERMT1 Synonyms:C20orf42,KIND1,URP1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9BQL6 |
| PRO Name | fermitin family homolog 1 (human) |
| Definition | A fermitin family homolog 1 that is encoded in the genome of human. |
| Short Label | hFERMT1 |
| Category | organism-gene |
Q9BQL6 (FERMT1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K148 | Acetylation | score1 | PhosphoSitePlus | |||
| S169 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S170 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
| T172 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
| S174 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S176 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S179 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
| Y191 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S361 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K371 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y392 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K435 | Acetylation | score1 | PhosphoSitePlus | |||
| Y452 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S502 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
| S506 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S520 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K592 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T663 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K671 | Ubiquitination | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S169 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S170 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| T172 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S174 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S179 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S502 | Phosphorylation | score0 | HPRD | 18669648 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K148 | N148 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S169 | C169 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S170 | Y170 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] | |
| T172 | A172 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S506 | Y506 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S520 | L520 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| K671 | R671 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |
DAG View