iPTMnet Report for Q9BQI6 (SLF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BQI6 / SLF1_HUMAN
Protein Name SMC5-SMC6 complex localization factor protein 1
Gene Name Name: SLF1
Synonyms:ANKRD32,BRCTD1;
Organism Homo sapiens (Human)

PRO ID PR:Q9BQI6
DAG View
PRO Name SMC5-SMC6 complex localization factor protein 1 (human)
Definition An SMC5-SMC6 complex localization factor protein 1 that is encoded in the genome of human.
Short Label hSLF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BQI6 (SLF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K16 Acetylation PhosphoSitePlus
K25 Acetylation PhosphoSitePlus
K25 Ubiquitination PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
T44 Phosphorylation PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
K78 Sumoylation PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
S158 Phosphorylation PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
S161 Phosphorylation PhosphoSitePlus
K183 Sumoylation PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
K235 Methylation PhosphoSitePlus
K235 Sumoylation PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
K247 Ubiquitination PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
K278 Sumoylation PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
K348 Sumoylation PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
K365 Sumoylation PhosphoSitePlus
K374 Ubiquitination PhosphoSitePlus
K396 Ubiquitination PhosphoSitePlus
S482 Phosphorylation PhosphoSitePlus
K565 Ubiquitination PhosphoSitePlus
S654 Phosphorylation PhosphoSitePlus
K717 Ubiquitination PhosphoSitePlus
K725 Ubiquitination PhosphoSitePlus
K731 Ubiquitination PhosphoSitePlus
T750 O-Glycosylation GlyGen 30379171
K753 Ubiquitination PhosphoSitePlus
K768 Ubiquitination PhosphoSitePlus
K788 Acetylation PhosphoSitePlus
K788 Ubiquitination PhosphoSitePlus
K797 Ubiquitination PhosphoSitePlus
K802 Ubiquitination PhosphoSitePlus
K806 Sumoylation PhosphoSitePlus
K806 Ubiquitination PhosphoSitePlus
K909 Ubiquitination PhosphoSitePlus
Y916 Phosphorylation PhosphoSitePlus
S919 Phosphorylation PhosphoSitePlus
K923 Ubiquitination PhosphoSitePlus
K931 Ubiquitination PhosphoSitePlus
T1017 Phosphorylation PhosphoSitePlus
K1020 Ubiquitination PhosphoSitePlus
K1026 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T44 Phosphorylation HPRD 18691976
S161 Phosphorylation HPRD 19691289


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S159 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K223 N223 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K278 I278 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K295 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K348 E348 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K374 E374 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K788 Q788 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K802 N802 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K806 E806 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]