iPTMnet Report for Q9BQF6 (SENP7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BQF6 / SENP7_HUMAN
Protein Name Sentrin-specific protease 7
Gene Name Name: SENP7
Synonyms:KIAA1707;
Organism Homo sapiens (Human)

PRO ID PR:Q9BQF6
DAG View
PRO Name sentrin-specific protease 7 (human)
Definition A sentrin-specific protease 7 that is encoded in the genome of human.
Short Label hSENP7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BQF6 (SENP7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 23186163
S12 Phosphorylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
K20 Methylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus   UniProt 19690332
S46 Phosphorylation PhosphoSitePlus
R83 Methylation PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
S92 Phosphorylation PhosphoSitePlus
T116 O-Glycosylation GlyGen 30379171
K148 Ubiquitination PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
S373 Phosphorylation PhosphoSitePlus   UniProt 23186163
S379 Phosphorylation HPRD 18452278
S407 Phosphorylation PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
S433 Phosphorylation PhosphoSitePlus   UniProt 24275569
S443 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S444 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
K459 Ubiquitination PhosphoSitePlus
K537 Ubiquitination PhosphoSitePlus
K698 Ubiquitination PhosphoSitePlus
K710 Ubiquitination PhosphoSitePlus
S720 Phosphorylation PhosphoSitePlus
S721 Phosphorylation PhosphoSitePlus
K815 Ubiquitination PhosphoSitePlus
S916 Phosphorylation PhosphoSitePlus
K973 Ubiquitination PhosphoSitePlus
K1039 Ubiquitination PhosphoSitePlus
K1046 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation HPRD 19413330
S443 Phosphorylation HPRD 18452278
S444 Phosphorylation HPRD 18452278
Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation PhosphoSitePlus
S12 Phosphorylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
S92 Phosphorylation PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus
T167 Phosphorylation PhosphoSitePlus
T230 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
S377 Phosphorylation PhosphoSitePlus
S378 Phosphorylation PhosphoSitePlus
T402 Phosphorylation PhosphoSitePlus
S635 Phosphorylation PhosphoSitePlus
S936 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S13 F13 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S46 P46 Biomuta DOID:363 / uterine cancer [ icgc ]
R83 Q83 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
R83 * Biomuta DOID:4362 / cervical cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
K90 T90 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
S233 F233 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
S373 N373 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S377 F377 Biomuta DOID:4159 / skin cancer [ cosmic ]
S443 F443 Biomuta DOID:4159 / skin cancer [ cosmic ]
K459 N459 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
K459 M459 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S635 F635 Biomuta DOID:4159 / skin cancer [ cosmic ]
S936 R936 Biomuta DOID:10534 / stomach cancer [ cosmic ]