iPTMnet Report for Q9BQC3 (DPH2)
Protein Information
| UniProt AC / UniProt ID | Q9BQC3 / DPH2_HUMAN |
| Protein Name | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 |
| Gene Name | Name: DPH2 Synonyms:DPH2L2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9BQC3 |
| PRO Name | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 (human) |
| Definition | A 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 that is encoded in the genome of human. |
| Short Label | hDPH2 |
| Category | organism-gene |
DAG ViewQ9BQC3 (DPH2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 22814378 | ||
| S7 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K146 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C157 | Methylation | score1 | IEDB | 31844290 | ||
| S188 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K223 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K256 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T307 | Phosphorylation | score1 | IEDB | 35494241 | ||
| K312 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S314 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S426 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S431 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T435 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648 | ||
| S445 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S446 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648 | ||
| S450 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S456 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T467 | O-Glycosylation | score1 | GlyGen | 32574038, 35132862, 30620550, ... | ||
| T467 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| T470 | O-Glycosylation | score1 | GlyGen | 32574038, 32938750, 30059200, ... | ||
| T470 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S474 | O-Glycosylation | score1 | GlyGen | 32574038, 35132862, 30620550, ... | ||
| S474 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S488 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 19690332, 20068231 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S314 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T435 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S445 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S446 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S456 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T467 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S488 | Phosphorylation | score0 | HPRD | 19651622, 20068231 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T207 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S217 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S218 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S228 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T239 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S260 | Phosphorylation | score0 | HPRD | 19651622, 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S7 | N7 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S228 | I228 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S260 | R260 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K312 | Q312 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S314 | G314 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S314 | T314 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S426 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S450 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| S456 | I456 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S488 | R488 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
