iPTMnet Report for Q9BQA1 (WDR77)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BQA1 / MEP50_HUMAN
Protein Name Methylosome protein WDR77
Gene Name Name: WDR77
Synonyms:MEP50;ORFNames:HKMT1069,Nbla10071;
Organism Homo sapiens (Human)

PRO ID PR:Q9BQA1
DAG View
PRO Name methylosome protein 50 (human)
Definition A methylosome protein 50 that is encoded in the genome of human.
Short Label hWDR77
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BQA1 (WDR77) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K3 Ubiquitination PhosphoSitePlus
T5 Phosphorylation P11802 (CDK4) neXtProt   phospho.ELM   PRO   PhosphoSitePlus   UniProt 23186163, 20951943, 18669648, ...24275569, 19690332, 20068231
S38 Phosphorylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
S48 Phosphorylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
C53 Methylation IEDB 31844290
K121 Ubiquitination PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
C148 Methylation IEDB 31844290
T171 Phosphorylation PhosphoSitePlus
C172 Methylation IEDB 31844290
S176 Phosphorylation PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
S181 Phosphorylation PhosphoSitePlus
C257 Methylation IEDB 31844290
S264 Phosphorylation P11802 (CDK4) neXtProt   PhosphoSitePlus 20951943
S306 Phosphorylation P11802 (CDK4) neXtProt   PhosphoSitePlus 20951943
S339 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T5 Phosphorylation HPRD 17322306, 18212344, 18767875, ...19651622, 18669648, 20068231, 17924679


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049677 (hWDR77/Phos:1) pT5 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K121 R121 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S176 F176 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S181 F181 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]