Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9BQ67 / GRWD1_HUMAN
Protein Name Glutamate-rich WD repeat-containing protein 1
Gene Name Name: GRWD1
Organism Homo sapiens (Human)

DAG View
PRO Name glutamate-rich WD repeat-containing protein 1 (human)
Definition A glutamate-rich WD repeat-containing protein 1 that is encoded in the genome of human.
Short Label hGRWD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9BQ67 (GRWD1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
T10 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
T13 Phosphorylation PhosphoSitePlus
S21 Phosphorylation PhosphoSitePlus
T24 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S25 Phosphorylation PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
Y33 Phosphorylation HPRD   phospho.ELM 18669648
T114 Phosphorylation HPRD   PhosphoSitePlus 17081983
S119 Phosphorylation HPRD   PhosphoSitePlus   UniProt 17081983, 20068231, 18452278
S122 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 17081983, 18452278
Y149 Phosphorylation PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
R181 Methylation PhosphoSitePlus
K237 Ubiquitination PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K333 Ubiquitination PhosphoSitePlus
K341 Sumoylation PhosphoSitePlus
K341 Ubiquitination PhosphoSitePlus
S344 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 23186163

PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P20963 (CD247) Y72 Q9BQ67 (GRWD1) unknown eFIP 24502978

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T10 R10 Biomuta DOID:2531 / hematologic cancer [ icgc ]
K333 E333 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S344 F344 Biomuta DOID:363 / uterine cancer [ tcga ]