iPTMnet Report for Q9BPU6 (DPYSL5)
Protein Information
UniProt AC / UniProt ID | Q9BPU6 / DPYL5_HUMAN |
Protein Name | Dihydropyrimidinase-related protein 5 |
Gene Name | Name: DPYSL5 Synonyms:CRMP5,ULIP6; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9BPU6 |
PRO Name | dihydropyrimidinase-related protein 5 (human) |
Definition | A dihydropyrimidinase-related protein 5 that is encoded in the genome of human. |
Short Label | hDPYSL5 |
Category | organism-gene |
Q9BPU6 (DPYSL5) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Phosphorylation | score1 | PRO | ||||
Y163 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y167 | Phosphorylation | score1 | PhosphoSitePlus | |||
K343 | Methylation | score1 | PhosphoSitePlus | |||
R361 | Methylation | score1 | PhosphoSitePlus | |||
Y388 | Phosphorylation | score1 | PhosphoSitePlus | |||
S466 | Phosphorylation | score1 | PhosphoSitePlus | |||
T470 | Phosphorylation | score1 | PhosphoSitePlus | |||
T481 | Phosphorylation | score1 | PhosphoSitePlus | |||
T509 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 17287340 | ||
T514 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 17287340 | ||
T516 | Phosphorylation | score4 | HPRD phospho.ELM PhosphoSitePlus Signor | 25040932, 17287340 | ||
T516 | Phosphorylation | P49841 (GSK3B) | score1 | Signor | 25040932 | |
S534 | Phosphorylation | score2 | HPRD phospho.ELM PRO PhosphoSitePlus | 17287340 | ||
S536 | Phosphorylation | score1 | PhosphoSitePlus | |||
S538 | Phosphorylation | score1 | PhosphoSitePlus | |||
S549 | Phosphorylation | score1 | PhosphoSitePlus | |||
R559 | Methylation | score1 | PhosphoSitePlus | |||
S560 | Phosphorylation | score1 | PhosphoSitePlus | |||
S561 | Phosphorylation | score1 | PhosphoSitePlus |
Proteoforms
PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
---|---|---|---|---|---|
PR:000047212 (hDPYSL5/Phos:1) | pS534 | PRO | |||
PR:000047213 (hDPYSL5/PhosTyr+) | p | PRO |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y167 | H167 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
T470 | A470 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
T514 | A514 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S560 | L560 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |