iPTMnet Report for Q99MK8 (Grk2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99MK8 / ARBK1_MOUSE
Protein Name Beta-adrenergic receptor kinase 1
Gene Name Name: Grk2
Synonyms:Adrbk1;
Organism Mus musculus (Mouse)

PRO ID PR:Q99MK8
DAG View
PRO Name beta-adrenergic receptor kinase 1 (mouse)
Definition A beta-adrenergic receptor kinase 1 that is encoded in the genome of mouse.
Short Label mGRK2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99MK8 (Grk2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y13 Phosphorylation PhosphoSitePlus
C72 S-Nitrosylation dbSNO 17482545, 22178444
Y86 Phosphorylation PhosphoSitePlus
Y92 Phosphorylation PhosphoSitePlus
C120 S-Nitrosylation dbSNO 17482545, 22178444
C340 S-Nitrosylation dbSNO 17482545, 22178444
K344 Ubiquitination PhosphoSitePlus
Y356 Phosphorylation PhosphoSitePlus
S389 Phosphorylation PhosphoSitePlus
C439 S-Nitrosylation dbSNO 17482545, 22178444
S487 Phosphorylation PhosphoSitePlus
C619 S-Nitrosylation dbSNO 17482545, 22178444
S670 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 23467820, 26932512, 31447681, ...21183079
S676 Phosphorylation PhosphoSitePlus
S685 Phosphorylation RLIMS-P 28381559


Q99MK8 (Grk2) as PTM Enzyme



Substrate Site Score Source PMID
O54943 (Per2) S545 PhosphoSitePlus 26279567
P09174 (Pde6g) T62 PhosphoSitePlus 11502744
P18762 (Adrb2) S355 PhosphoSitePlus 18056263
P18762 (Adrb2) S356 PhosphoSitePlus 18056263
P35569 (Irs1) S612 PhosphoSitePlus 15994203
P35569 (Irs1) S635 PhosphoSitePlus 15994203