iPTMnet Report for Q99988 (GDF15)
Protein Information
| UniProt AC / UniProt ID | Q99988 / GDF15_HUMAN |
| Protein Name | Growth/differentiation factor 15 precursor |
| Gene Name | Name: GDF15 Synonyms:MIC1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q99988 |
| PRO Name | growth/differentiation factor 15 (human) |
| Definition | A growth/differentiation factor 15 that is encoded in the genome of human. |
| Short Label | hGDF15 |
| Category | organism-gene |
DAG ViewQ99988 (GDF15) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S36 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| S39 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| S44 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
| Y60 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| N70 | N-Glycosylation | score1 | GlyGen | 23090970, 24190977 | ||
| S146 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K265 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K303 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S36 | R36 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S44 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| N70 | S70 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
