iPTMnet Report for Q99963 (SH3GL3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99963 / SH3G3_HUMAN
Protein Name Endophilin-A3
Gene Name Name: SH3GL3
Synonyms:CNSA3,SH3D2C;
Organism Homo sapiens (Human)

PRO ID PR:Q99963
DAG View
PRO Name endophilin-A3 (human)
Definition An endophilin-A3 that is encoded in the genome of human.
Short Label hSH3GL3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99963 (SH3GL3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus
T55 O-Glycosylation GlyGen 28657654
T83 Phosphorylation PhosphoSitePlus
Y86 Phosphorylation PhosphoSitePlus
Y168 Phosphorylation PhosphoSitePlus
S238 Phosphorylation IEDB 35494241
S248 Phosphorylation PhosphoSitePlus
Y255 Phosphorylation PhosphoSitePlus
K261 Acetylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
S265 Phosphorylation PhosphoSitePlus   UniProt 23186163
K277 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T83 A83 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T83 I83 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S238 I238 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S238 N238 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S248 T248 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S248 P248 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S248 F248 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S264 P264 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S265 R265 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K277 T277 Biomuta DOID:9256 / colorectal cancer [ cosmic ]