iPTMnet Report for Q99956 (DUSP9)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99956 / DUS9_HUMAN
Protein Name Dual specificity protein phosphatase 9
Gene Name Name: DUSP9
Synonyms:MKP4;
Organism Homo sapiens (Human)

PRO ID PR:Q99956
DAG View
PRO Name dual specificity protein phosphatase 9 (human)
Definition A dual specificity protein phosphatase 9 that is encoded in the genome of human.
Short Label hDUSP9
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99956 (DUSP9) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S16 Phosphorylation PhosphoSitePlus   UniProt 23186163
S58 Phosphorylation RLIMS-P 21908610
T193 Phosphorylation PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus
Y232 Phosphorylation PhosphoSitePlus
T237 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus   UniProt 23186163
K324 Ubiquitination PhosphoSitePlus
S325 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 20068231, 18220336
S328 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S351 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
S356 Phosphorylation HPRD 20068231
S361 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T372 Phosphorylation HPRD   phospho.ELM 18669648
T374 Phosphorylation HPRD 20068231
S375 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S16 L16 Biomuta DOID:3571 / liver cancer [ cosmic ]
S325 Y325 Biomuta DOID:363 / uterine cancer [ icgc ]
S356 I356 Biomuta DOID:1324 / lung cancer [ cosmic ]
T372 N372 Biomuta DOID:1324 / lung cancer [ cosmic ]
T374 N374 Biomuta DOID:1324 / lung cancer [ cosmic ]