iPTMnet Report for Q99836 (MYD88)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99836 / MYD88_HUMAN
Protein Name Myeloid differentiation primary response protein MyD88
Gene Name Name: MYD88
Organism Homo sapiens (Human)

PRO ID PR:Q99836
DAG View
PRO Name myeloid differentiation primary response protein MyD88 (human)
Definition A myeloid differentiation primary response protein MyD88 that is encoded in the genome of human.
Short Label hMYD88
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99836 (MYD88) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K95 Ubiquitination PhosphoSitePlus
C113 S-Nitrosylation dbSNO 18086890, 22178444
K115 Ubiquitination PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
C216 S-Nitrosylation dbSNO 18086890, 22178444
S230 O-Glycosylation GlyGen 30620550
K231 Ubiquitination PhosphoSitePlus
C233 Methylation IEDB 31844290
K238 Ubiquitination PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus   UniProt 23186163
K250 Ubiquitination PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
Y257 Phosphorylation PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
Y276 Phosphorylation PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q15109 (AGER) S391 Q99836 (MYD88) increased_association eFIP 32670078


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000027493 (hIRAK1/iso:1/Phos:4) NOT Interaction PR:Q99836 (hMYD88) PRO 14625308
PR:P51617-1 (hIRAK1/iso:1) Interaction PR:Q99836 (hMYD88) PRO 14625308
PR:Q9Y616-1 (hIRAK3/iso:1) Interaction PR:Q99836 (hMYD88) PRO 10383454