Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99816 / TS101_HUMAN
Protein Name Tumor susceptibility gene 101 protein
Gene Name Name: TSG101
Organism Homo sapiens (Human)

PRO ID PR:Q99816
DAG View
PRO Name tumor susceptibility gene 101 protein (human)
Definition A tumor susceptibility gene 101 protein that is encoded in the genome of human.
Short Label hTSG101
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99816 (TSG101) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378
S6 Phosphorylation PhosphoSitePlus
K14 Acetylation PhosphoSitePlus
Y15 Phosphorylation PhosphoSitePlus
K16 Acetylation PhosphoSitePlus
Y32 Phosphorylation PhosphoSitePlus
S48 Phosphorylation PhosphoSitePlus
T56 Phosphorylation PhosphoSitePlus
Y63 Phosphorylation PhosphoSitePlus
K90 Acetylation PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
T220 Phosphorylation PhosphoSitePlus   UniProt 23186163
S222 Phosphorylation PhosphoSitePlus
T225 Phosphorylation PhosphoSitePlus
K237 Acetylation PhosphoSitePlus
K237 Ubiquitination PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
K286 Ubiquitination PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
K293 Ubiquitination PhosphoSitePlus
S299 Phosphorylation PhosphoSitePlus
S300 Phosphorylation PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
S309 Phosphorylation PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
Y390 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
Site PTM Type PTM Enzyme Score Source PMID
T220 Phosphorylation HPRD 19007248
S299 Phosphorylation HPRD 20068231
S300 Phosphorylation HPRD 20068231
Y390 Phosphorylation HPRD 18083107


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y15 C15 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S300 P300 Biomuta DOID:9256 / colorectal cancer [ tcga ]