iPTMnet Report for Q99767 (APBA2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99767 / APBA2_HUMAN
Protein Name Amyloid-beta A4 precursor protein-binding family A member 2
Gene Name Name: APBA2
Synonyms:MINT2,X11L;
Organism Homo sapiens (Human)

PRO ID PR:Q99767
DAG View
PRO Name amyloid-beta A4 precursor protein-binding family A member 2 (human)
Definition An amyloid-beta A4 precursor protein-binding family A member 2 that is encoded in the genome of human.
Short Label hAPBA2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99767 (APBA2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y186 Phosphorylation PhosphoSitePlus
Y193 Phosphorylation PhosphoSitePlus
Y196 Phosphorylation PhosphoSitePlus
Y197 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus   UniProt 23186163
S236 Phosphorylation PhosphoSitePlus   RLIMS-P 19222704
S238 Phosphorylation PhosphoSitePlus   RLIMS-P 19222704
S283 Phosphorylation PhosphoSitePlus
T306 Phosphorylation PhosphoSitePlus
K346 Ubiquitination PhosphoSitePlus
S478 Phosphorylation PhosphoSitePlus
S480 Phosphorylation PhosphoSitePlus
S609 Phosphorylation PhosphoSitePlus
S613 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S208 Phosphorylation HPRD 15345747
S478 Phosphorylation HPRD 19413330
S480 Phosphorylation HPRD 19413330, 19664995


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S11 N11 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
Y196 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S238 C238 Biomuta DOID:1324 / lung cancer [ cosmic ]
S283 L283 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1793 / pancreatic cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic, icgc ]
S478 L478 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S609 L609 Biomuta DOID:363 / uterine cancer [ icgc ]