iPTMnet Report for Q99733 (NAP1L4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99733 / NP1L4_HUMAN
Protein Name Nucleosome assembly protein 1-like 4
Gene Name Name: NAP1L4
Synonyms:NAP2;
Organism Homo sapiens (Human)

PRO ID PR:Q99733
DAG View
PRO Name nucleosome assembly protein 1-like 4 (human)
Definition A nucleosome assembly protein 1-like 4 that is encoded in the genome of human.
Short Label hNAP1L4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99733 (NAP1L4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 21406692, 22223895, ...20068231
S5 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...20068231
S7 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 20068231
S12 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 20068231
S14 Phosphorylation PhosphoSitePlus
K19 Ubiquitination PhosphoSitePlus
T24 Phosphorylation PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
T28 Phosphorylation PhosphoSitePlus
T51 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S53 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 16565220
S54 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231, 16565220
Y55 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T58 Phosphorylation PhosphoSitePlus   UniProt 23186163
K61 Ubiquitination PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
Y85 Phosphorylation PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
T111 Phosphorylation PhosphoSitePlus
T117 Phosphorylation PhosphoSitePlus
S121 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S125 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18318008, 18669648, 17287340, 16565220, 19690332, 20068231
S139 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
K140 Ubiquitination PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
T150 Phosphorylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
Y215 Phosphorylation PhosphoSitePlus
K255 Acetylation PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
K256 Acetylation PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
S299 Phosphorylation PhosphoSitePlus
S304 Phosphorylation PhosphoSitePlus   UniProt 19690332
S309 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation HPRD 19413330, 19651622, 17081983, ...20068231, 19007248
S7 Phosphorylation HPRD 19413330, 19651622, 20068231
S12 Phosphorylation HPRD 19413330, 19651622, 20058876, ...20068231
S14 Phosphorylation HPRD 19651622, 20068231
T51 Phosphorylation HPRD 17322306, 18767875, 19651622, ...18669648, 20068231, 17924679
S53 Phosphorylation HPRD 19651622, 18669648, 20068231, ...16565220
S54 Phosphorylation HPRD 19651622, 18669648, 20068231, ...16565220
Y55 Phosphorylation HPRD 18669648
T58 Phosphorylation HPRD 20068231
S121 Phosphorylation HPRD 18669648, 18452278, 19664995, ...17081983
S125 Phosphorylation HPRD 19413330, 17287340, 20230923, ...19664994, 19664995, 18452278, 19651622, 18510355, 18669648, 20166139, 16565220, 19415658, 20068231
S139 Phosphorylation HPRD 17287340


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S7 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K19 T19 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K26 N26 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T111 I111 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
T150 M150 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ icgc ]
S299 Y299 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S299 F299 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]