iPTMnet Report for Q99729 (HNRNPAB)
Protein Information
UniProt AC / UniProt ID | Q99729 / ROAA_HUMAN |
Protein Name | Heterogeneous nuclear ribonucleoprotein A/B |
Gene Name | Name: HNRNPAB Synonyms:ABBP1,HNRPAB; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q99729 |
PRO Name | heterogeneous nuclear ribonucleoprotein A/B (human) |
Definition | A heterogeneous nuclear ribonucleoprotein A/B that is encoded in the genome of human. |
Short Label | hHNRNPAB |
Category | organism-gene |
Q99729 (HNRNPAB) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S81 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
K82 | Acetylation | score1 | PhosphoSitePlus | |||
K82 | Ubiquitination | score1 | PhosphoSitePlus | |||
K83 | Ubiquitination | score1 | PhosphoSitePlus | |||
K86 | Acetylation | score1 | PhosphoSitePlus | |||
K86 | Ubiquitination | score1 | PhosphoSitePlus | |||
K91 | Acetylation | score1 | PhosphoSitePlus | |||
K91 | Ubiquitination | score1 | PhosphoSitePlus | |||
C98 | Methylation | score1 | IEDB | 31844290 | ||
C98 | S-Nitrosylation | score0 | dbSNO | 2212679, 22126794 | ||
T99 | Phosphorylation | score1 | PhosphoSitePlus | |||
K101 | Acetylation | score1 | PhosphoSitePlus | |||
K101 | Ubiquitination | score1 | PhosphoSitePlus | |||
K118 | Ubiquitination | score1 | PhosphoSitePlus | |||
S122 | O-Glycosylation | score1 | GlyGen | 30444036, 34725712, 33214551, ... | ||
K125 | Ubiquitination | score1 | PhosphoSitePlus | |||
K130 | Ubiquitination | score1 | PhosphoSitePlus | |||
K190 | Ubiquitination | score1 | PhosphoSitePlus | |||
K215 | Acetylation | score1 | PhosphoSitePlus | |||
K215 | Ubiquitination | score1 | PhosphoSitePlus | |||
K223 | Ubiquitination | score1 | PhosphoSitePlus | |||
K227 | Ubiquitination | score1 | PhosphoSitePlus | |||
K232 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y235 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y240 | Phosphorylation | score1 | PhosphoSitePlus | |||
S242 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 16964243, ... | ||
R245 | Methylation | score1 | PhosphoSitePlus | |||
R248 | Methylation | score1 | PhosphoSitePlus | |||
R250 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
G251 | Methylation | score1 | UniProt | 24129315 | ||
R253 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
G254 | Methylation | score1 | UniProt | 24129315 | ||
S255 | Phosphorylation | score1 | UniProt | 21406692, 20068231 | ||
G256 | Phosphorylation | score1 | UniProt | 21406692, 20068231 | ||
G271 | Acetylation | score1 | UniProt | 19608861 | ||
Y272 | Acetylation | score1 | UniProt | 19608861 | ||
Y300 | Phosphorylation | score1 | PhosphoSitePlus | |||
T314 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y316 | Phosphorylation | score1 | PhosphoSitePlus | |||
R321 | Methylation | score1 | PhosphoSitePlus | |||
R322 | Methylation | score4 | PhosphoSitePlus UniProt | 24129315, 15782174 | ||
Y329 | Phosphorylation | score1 | PhosphoSitePlus | |||
K330 | Acetylation | score1 | PhosphoSitePlus | |||
K330 | Methylation | score1 | PhosphoSitePlus | |||
Y332 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T100 | Phosphorylation | score0 | HPRD | 19664994 | ||
K155 | Ubiquitination | score1 | PhosphoSitePlus | |||
K169 | Acetylation | score1 | PhosphoSitePlus | |||
K169 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y235 | Phosphorylation | score0 | HPRD | 20068231 | ||
Y240 | Phosphorylation | score0 | HPRD | 20068231 | ||
S242 | Phosphorylation | score0 | HPRD | 19413330, 18691976, 16964243, ... | ||
Y332 | Phosphorylation | score0 | HPRD | 20068230 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
S28 | Phosphorylation | score1 | PhosphoSitePlus | |||
T100 | Phosphorylation | score0 | HPRD | 19664994 | ||
K155 | Ubiquitination | score1 | PhosphoSitePlus | |||
K169 | Acetylation | score1 | PhosphoSitePlus | |||
K169 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y235 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17287340, 20068231 | ||
Y240 | Phosphorylation | score0 | HPRD | 20068231 | ||
S242 | Phosphorylation | score0 | HPRD | 19413330, 18691976, 16964243, ... | ||
R250 | Methylation | score1 | PhosphoSitePlus | |||
R253 | Methylation | score1 | PhosphoSitePlus | |||
S255 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
T267 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y269 | Phosphorylation | score1 | PhosphoSitePlus | |||
K271 | Acetylation | score1 | PhosphoSitePlus | |||
K271 | Ubiquitination | score1 | PhosphoSitePlus | |||
S272 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y285 | Phosphorylation | score0 | HPRD | 20068230 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S2 | L2 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
S28 | A28 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
K169 | N169 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
Y240 | H240 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
R250 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
R253 | Q253 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K271 | N271 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
S272 | R272 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
Y285 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y285 | H285 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y285 | S285 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
Y332 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y332 | H332 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y332 | S332 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic, icgc, cosmic ] |