iPTMnet Report for Q99729 (HNRNPAB)
Protein Information
| UniProt AC / UniProt ID | Q99729 / ROAA_HUMAN |
| Protein Name | Heterogeneous nuclear ribonucleoprotein A/B |
| Gene Name | Name: HNRNPAB Synonyms:ABBP1,HNRPAB; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q99729 |
| PRO Name | heterogeneous nuclear ribonucleoprotein A/B (human) |
| Definition | A heterogeneous nuclear ribonucleoprotein A/B that is encoded in the genome of human. |
| Short Label | hHNRNPAB |
| Category | organism-gene |
Q99729 (HNRNPAB) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S81 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
| K82 | Acetylation | score1 | PhosphoSitePlus | |||
| K82 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K83 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K86 | Acetylation | score1 | PhosphoSitePlus | |||
| K86 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K91 | Acetylation | score1 | PhosphoSitePlus | |||
| K91 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C98 | Methylation | score1 | IEDB | 31844290 | ||
| C98 | S-Nitrosylation | score0 | dbSNO | 2212679, 22126794 | ||
| T99 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K101 | Acetylation | score1 | PhosphoSitePlus | |||
| K101 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K118 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S122 | O-Glycosylation | score1 | GlyGen | 30444036, 34725712, 33214551, ... | ||
| K125 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K130 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K190 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K215 | Acetylation | score1 | PhosphoSitePlus | |||
| K215 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K223 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K227 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K232 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y235 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y240 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S242 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 16964243, ... | ||
| R245 | Methylation | score1 | PhosphoSitePlus | |||
| R248 | Methylation | score1 | PhosphoSitePlus | |||
| R250 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
| G251 | Methylation | score1 | UniProt | 24129315 | ||
| R253 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
| G254 | Methylation | score1 | UniProt | 24129315 | ||
| S255 | Phosphorylation | score1 | UniProt | 21406692, 20068231 | ||
| G256 | Phosphorylation | score1 | UniProt | 21406692, 20068231 | ||
| G271 | Acetylation | score1 | UniProt | 19608861 | ||
| Y272 | Acetylation | score1 | UniProt | 19608861 | ||
| Y300 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T314 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y316 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R321 | Methylation | score1 | PhosphoSitePlus | |||
| R322 | Methylation | score4 | PhosphoSitePlus UniProt | 24129315, 15782174 | ||
| Y329 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K330 | Acetylation | score1 | PhosphoSitePlus | |||
| K330 | Methylation | score1 | PhosphoSitePlus | |||
| Y332 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T100 | Phosphorylation | score0 | HPRD | 19664994 | ||
| K155 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K169 | Acetylation | score1 | PhosphoSitePlus | |||
| K169 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y235 | Phosphorylation | score0 | HPRD | 20068231 | ||
| Y240 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S242 | Phosphorylation | score0 | HPRD | 19413330, 18691976, 16964243, ... | ||
| Y332 | Phosphorylation | score0 | HPRD | 20068230 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S28 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T100 | Phosphorylation | score0 | HPRD | 19664994 | ||
| K155 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K169 | Acetylation | score1 | PhosphoSitePlus | |||
| K169 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y235 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17287340, 20068231 | ||
| Y240 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S242 | Phosphorylation | score0 | HPRD | 19413330, 18691976, 16964243, ... | ||
| R250 | Methylation | score1 | PhosphoSitePlus | |||
| R253 | Methylation | score1 | PhosphoSitePlus | |||
| S255 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| T267 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y269 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K271 | Acetylation | score1 | PhosphoSitePlus | |||
| K271 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S272 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y285 | Phosphorylation | score0 | HPRD | 20068230 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S2 | L2 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| S28 | A28 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| K169 | N169 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| Y240 | H240 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| R250 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| R253 | Q253 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K271 | N271 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| S272 | R272 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| Y285 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| Y285 | H285 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| Y285 | S285 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| Y332 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| Y332 | H332 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| Y332 | S332 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic, icgc, cosmic ] |
DAG View