Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99719 / SEPT5_HUMAN
Protein Name Septin-5
Gene Name Name: SEPT5
Synonyms:PNUTL1;
Organism Homo sapiens (Human)

PRO ID PR:Q99719
DAG View
PRO Name septin-5 (human)
Definition A septin-5 that is encoded in the genome of human.
Short Label hSEPT5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99719 (SEPT5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R6 Methylation PhosphoSitePlus
T13 Phosphorylation PhosphoSitePlus
Y24 Phosphorylation PhosphoSitePlus
T29 Phosphorylation PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
S225 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18088087, 23186163, 19690332
S249 Phosphorylation PhosphoSitePlus
T251 Phosphorylation PhosphoSitePlus
K318 Ubiquitination PhosphoSitePlus
S327 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 18385322, 23186163, 19690332
T336 Phosphorylation PhosphoSitePlus
T341 Phosphorylation PhosphoSitePlus
K343 Ubiquitination PhosphoSitePlus
K363 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S225 Phosphorylation HPRD 19651622, 20166139, 18088087, ...20230923
S327 Phosphorylation HPRD 15345747
T336 Phosphorylation HPRD 15345747
Site PTM Type PTM Enzyme Score Source PMID
S17 Phosphorylation Q00535 (CDK5) neXtProt   PhosphoSitePlus 17224448
R24 Methylation PhosphoSitePlus
Y33 Phosphorylation PhosphoSitePlus
S234 Phosphorylation HPRD 19651622, 20166139, 18088087, ...20230923


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T13 N13 Biomuta DOID:3571 / liver cancer [ icgc ]
K41 N41 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S225 L225 Biomuta DOID:3070 / malignant glioma [ tcga ]