iPTMnet Report for Q99715 (COL12A1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99715 / COCA1_HUMAN
Protein Name Collagen alpha-1(XII) chain precursor
Gene Name Name: COL12A1
Synonyms:COL12A1L;
Organism Homo sapiens (Human)

PRO ID PR:Q99715
DAG View
PRO Name collagen alpha-1(XII) chain (human)
Definition A collagen alpha-1(XII) chain that is encoded in the genome of human.
Short Label hCOL12A1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99715 (COL12A1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T67 Phosphorylation PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
T217 Phosphorylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
S329 O-Glycosylation GlyGen   UniProt 32337544
K458 Acetylation PhosphoSitePlus
K535 Acetylation PhosphoSitePlus
K535 Ubiquitination PhosphoSitePlus
K730 Ubiquitination PhosphoSitePlus
S765 Phosphorylation PhosphoSitePlus
T778 Phosphorylation PhosphoSitePlus
T786 Phosphorylation PhosphoSitePlus
T802 Phosphorylation PhosphoSitePlus
K1003 Ubiquitination PhosphoSitePlus
T1082 Phosphorylation PhosphoSitePlus
T1099 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T1106 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
K1115 Ubiquitination PhosphoSitePlus
K1118 Ubiquitination PhosphoSitePlus
T1120 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T1124 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T1180 O-Glycosylation GlyGen 30459171
T1181 O-Glycosylation GlyGen 30459171
S1223 Phosphorylation PhosphoSitePlus
S1261 Phosphorylation PhosphoSitePlus
T1292 Phosphorylation PhosphoSitePlus
K1311 Ubiquitination PhosphoSitePlus
S1312 Phosphorylation PhosphoSitePlus
T1397 Phosphorylation PhosphoSitePlus
Y1419 Phosphorylation PhosphoSitePlus
S1433 Phosphorylation PhosphoSitePlus
S1438 Phosphorylation PhosphoSitePlus
Y1450 Phosphorylation PhosphoSitePlus
T1743 O-Glycosylation GlyGen 22661428
T1743 Phosphorylation PhosphoSitePlus
T1748 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T1749 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 22661428
N1763 N-Glycosylation GlyGen 23090970, 29741879, 24190977
Y1897 Phosphorylation PhosphoSitePlus
T2062 Phosphorylation PhosphoSitePlus
S2125 Phosphorylation PhosphoSitePlus
Y2146 Phosphorylation PhosphoSitePlus
N2206 N-Glycosylation GlyGen 29741879
T2231 Phosphorylation PhosphoSitePlus
K2236 Acetylation PhosphoSitePlus
T2243 Phosphorylation PhosphoSitePlus
T2295 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
T2299 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
T2303 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
T2309 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
K2377 Ubiquitination PhosphoSitePlus
T2433 Phosphorylation PhosphoSitePlus
S2437 Phosphorylation PhosphoSitePlus
N2528 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
S2536 Phosphorylation PhosphoSitePlus
S2541 Phosphorylation PhosphoSitePlus
S2591 Phosphorylation PhosphoSitePlus
K2605 Ubiquitination PhosphoSitePlus
K2675 Ubiquitination PhosphoSitePlus
N2679 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
K2690 Ubiquitination PhosphoSitePlus
S2861 Phosphorylation PhosphoSitePlus
S2864 Phosphorylation PhosphoSitePlus
S2952 Phosphorylation PhosphoSitePlus
S2994 Phosphorylation PhosphoSitePlus
Y3043 Phosphorylation PhosphoSitePlus
S3062 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T67 Phosphorylation HPRD 20068231
S273 Phosphorylation HPRD 20068231
T509 Phosphorylation HPRD 20068231
N2528 N-Glycosylation PRO 29741879
S2616 Phosphorylation HPRD 20068231
N2679 N-Glycosylation PRO 29741879
S2952 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S1452 Phosphorylation HPRD 20068231
S1788 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S329 I329 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K730 R730 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K730 E730 Biomuta DOID:3571 / liver cancer [ cosmic ]
T1099 N1099 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S1312 L1312 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1438 C1438 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T1748 A1748 Biomuta DOID:363 / uterine cancer [ icgc ]
Y1897 C1897 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
N2206 I2206 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T2309 N2309 Biomuta DOID:3571 / liver cancer [ cosmic ]
T2433 M2433 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S2437 F2437 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S2536 A2536 Biomuta DOID:4159 / skin cancer [ cosmic ]
S2541 C2541 Biomuta DOID:4159 / skin cancer [ cosmic ]
S2591 R2591 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K2605 Q2605 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K2675 N2675 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S2861 G2861 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ]
S2861 R2861 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S2864 F2864 Biomuta DOID:4159 / skin cancer [ cosmic ]
S2994 L2994 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y3043 * Biomuta [ cosmic ]