iPTMnet Report for Q99665 (IL12RB2)
Protein Information
| UniProt AC / UniProt ID | Q99665 / I12R2_HUMAN |
| Protein Name | Interleukin-12 receptor subunit beta-2 precursor |
| Gene Name | Name: IL12RB2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q99665 |
| PRO Name | interleukin-12 receptor subunit beta-2 (human) |
| Definition | An interleukin-12 receptor subunit beta-2 that is encoded in the genome of human. |
| Short Label | hIL12RB2 |
| Category | organism-gene |
DAG ViewQ99665 (IL12RB2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y259 | Phosphorylation | score1 | IEDB | 35494241 | ||
| S295 | Phosphorylation | score1 | IEDB | 31848261 | ||
| T390 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S630 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S749 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K768 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y800 | Phosphorylation | score4 | IntAct UniProt | 10415122, 14559241, 9890938 | ||
| S859 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S295 | F295 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S749 | T749 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| K768 | E768 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] |
