iPTMnet Report for Q99650 (OSMR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99650 / OSMR_HUMAN
Protein Name Oncostatin-M-specific receptor subunit beta precursor
Gene Name Name: OSMR
Synonyms:OSMRB;
Organism Homo sapiens (Human)

PRO ID PR:Q99650
DAG View
PRO Name oncostatin-M-specific receptor subunit beta (human)
Definition An oncostatin-M-specific receptor subunit beta that is encoded in the genome of human.
Short Label hOSMR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99650 (OSMR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T33 Phosphorylation PhosphoSitePlus
N42 N-Glycosylation GlyGen 29391424
N84 N-Glycosylation GlyGen 29391424
K115 Ubiquitination PhosphoSitePlus
Y168 Phosphorylation PhosphoSitePlus
N176 N-Glycosylation GlyGen 23090970, 29671580, 29391424, ...24190977
Y180 Phosphorylation PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
N221 N-Glycosylation GlyGen 29391424
K241 Ubiquitination PhosphoSitePlus
K251 Ubiquitination PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
N326 N-Glycosylation GlyGen 23090970, 29391424, 24190977
N345 N-Glycosylation GlyGen 29391424
N361 N-Glycosylation GlyGen 29391424
N380 N-Glycosylation GlyGen 23090970, 29391424, 24190977
S382 Phosphorylation PhosphoSitePlus
Y389 Phosphorylation PhosphoSitePlus
K615 Ubiquitination PhosphoSitePlus
K677 Ubiquitination PhosphoSitePlus
K688 Ubiquitination PhosphoSitePlus
Y689 Phosphorylation PhosphoSitePlus
K767 Ubiquitination PhosphoSitePlus
K779 Ubiquitination PhosphoSitePlus
S784 Phosphorylation PhosphoSitePlus
K787 Ubiquitination PhosphoSitePlus
K789 Ubiquitination PhosphoSitePlus
S800 Phosphorylation PhosphoSitePlus
K812 Ubiquitination PhosphoSitePlus
K817 Ubiquitination PhosphoSitePlus
K825 Ubiquitination PhosphoSitePlus
S826 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T828 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T830 Phosphorylation phospho.ELM 18669648
K834 Ubiquitination PhosphoSitePlus
Y837 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
Y839 Phosphorylation PhosphoSitePlus
K845 Ubiquitination PhosphoSitePlus
C853 Methylation IEDB 31844290
T860 Phosphorylation PhosphoSitePlus
Y861 Phosphorylation PhosphoSitePlus
S877 Phosphorylation PhosphoSitePlus
K879 Ubiquitination PhosphoSitePlus
S882 O-Glycosylation GlyGen 29351928
S889 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K895 Ubiquitination PhosphoSitePlus
K899 Ubiquitination PhosphoSitePlus
Y901 Phosphorylation PhosphoSitePlus
Y917 Phosphorylation PhosphoSitePlus
K929 Ubiquitination PhosphoSitePlus
Y945 Phosphorylation PhosphoSitePlus
Y978 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N176 N-Glycosylation PRO 29671580
Y379 Phosphorylation HPRD 20068231
S382 Phosphorylation HPRD 20068231
S605 Phosphorylation HPRD 20068231
S826 Phosphorylation HPRD 18669648, 20068231
T828 Phosphorylation HPRD 18669648
T830 Phosphorylation HPRD 18669648
Y837 Phosphorylation HPRD 18083107
S889 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N42 Y42 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y168 H168 Biomuta DOID:4159 / skin cancer [ cosmic ]
N176 T176 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K209 E209 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K269 Q269 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K285 N285 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
N326 T326 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y379 C379 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y379 H379 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S382 F382 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S605 C605 Biomuta DOID:3571 / liver cancer [ cosmic ]
K615 R615 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K677 R677 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S784 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K787 T787 Biomuta DOID:263 / kidney cancer [ cosmic ]
K787 Q787 Biomuta DOID:363 / uterine cancer [ icgc ]
K817 R817 Biomuta DOID:2021 / placenta cancer [ cosmic ]
K845 N845 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
C853 G853 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T860 S860 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S877 F877 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K879 E879 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S882 R882 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S889 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y901 C901 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y945 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]