iPTMnet Report for Q99638 (RAD9A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99638 / RAD9A_HUMAN
Protein Name Cell cycle checkpoint control protein RAD9A
Gene Name Name: RAD9A
Organism Homo sapiens (Human)

PRO ID PR:Q99638
DAG View
PRO Name cell cycle checkpoint control protein RAD9A (human)
Definition A cell cycle checkpoint control protein RAD9A that is encoded in the genome of human.
Short Label hRAD9A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99638 (RAD9A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K2 Methylation PhosphoSitePlus
K15 Ubiquitination PhosphoSitePlus
Y28 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 11971963, 18769057
Y28 Phosphorylation A0A173G4P4 (Abl fusion) phospho.ELM 11971963
Y28 Phosphorylation P00519 (ABL1) HPRD   neXtProt   PhosphoSitePlus   Signor 11971963
K96 Ubiquitination PhosphoSitePlus
T167 Phosphorylation PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus
S266 Phosphorylation HPRD 20068231
T268 Phosphorylation PhosphoSitePlus
S270 Phosphorylation HPRD   phospho.ELM 18669648, 20068231
S272 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 26658951, 11278446, 20305300, ...12709442, 12734188, 18669648, 11551919, 17511890, 22453082
S272 Phosphorylation Q13315 (ATM) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 11278446, 20305300, 12734188, ...12709442, 18669648, 22453082
S277 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 19651622, 12734188, 12709442, ...17322306, 18669648, 29254517, 24098381, 19690332, 20068231
S277 Phosphorylation P06493 (CDK1) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 12734188
T292 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 11551919, 12734188, 29254517
T292 Phosphorylation P06493 (CDK1) phospho.ELM   PhosphoSitePlus   Signor 12734188
T313 Phosphorylation RLIMS-P 29254517
S324 Phosphorylation PhosphoSitePlus
S326 Phosphorylation PhosphoSitePlus   RLIMS-P 29254517
S328 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 23186163, 12734188, 23946870, ...12709442, 26860083, 19651622, 24376897, 23028682, 29254517, 18940270
S328 Phosphorylation P06493 (CDK1) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 12734188
S328 Phosphorylation P24941 (CDK2) PhosphoSitePlus   Signor 23028682
S328 Phosphorylation Q9UKI8 (TLK1) phospho.ELM   PhosphoSitePlus   Signor 24376897, 18940270
S336 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 29254517, 12734188, 12709442
S336 Phosphorylation P06493 (CDK1) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 12734188
S341 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 20545769, 12709442, 25091155, ...22925454
S341 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 20545769
S350 Phosphorylation PhosphoSitePlus
T351 Phosphorylation PhosphoSitePlus
T355 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 24376897, 12709442, 12734188, ...26860083
T355 Phosphorylation P06493 (CDK1) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 12734188
T355 Phosphorylation Q9UKI8 (TLK1) PhosphoSitePlus   Signor 24376897
S363 Phosphorylation PhosphoSitePlus
S375 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 17081983, 12709442, ...19651622, 18669648, 19690332, 20068231
S380 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 12709442, 20068231, 17081983
S387 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 19413330, 21406692, 23186163, ...17081983, 20858457, 20545769, 30295604, 12709442, 12734188, 19651622, 18669648, 25091155, 26658951, 20724438, 19690332, 20068231, 22925454
S387 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 20545769, 20724438


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q99638 (RAD9A) S341 Q92547 (TOPBP1) unknown eFIP 26658951
Phosphorylation Q99638 (RAD9A) S328 P10415 (BCL2) unknown eFIP 23028682
Phosphorylation Q99638 (RAD9A) S387 Q92547 (TOPBP1) unknown eFIP 30295604
Phosphorylation Q99638 (RAD9A) T292 P53350 (PLK1) unknown eFIP 29254517
Phosphorylation Q99638 (RAD9A) S341 Q92547 (TOPBP1) unknown eFIP 25091155
Phosphorylation Q99638 (RAD9A) S328 Q07817 (BCL2L1) unknown eFIP 23028682


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K15 E15 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S266 L266 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S272 C272 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S277 T277 Biomuta DOID:1612 / breast cancer [ cosmic ]