iPTMnet Report for Q99627 (COPS8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99627 / CSN8_HUMAN
Protein Name COP9 signalosome complex subunit 8
Gene Name Name: COPS8
Synonyms:CSN8;
Organism Homo sapiens (Human)

PRO ID PR:Q99627
DAG View
PRO Name COP9 signalosome complex subunit 8 (human)
Definition A COP9 signalosome complex subunit 8 that is encoded in the genome of human.
Short Label hCOPS8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99627 (COPS8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K65 Ubiquitination PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
S175 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18850735, 18669648, ...24275569, 20068231
K178 Ubiquitination PhosphoSitePlus
S183 O-Glycosylation GlyGen 28510447, 35254053
Y203 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S175 Phosphorylation HPRD 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S126 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K65 N65 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]