iPTMnet Report for Q99618 (CDCA3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99618 / CDCA3_HUMAN
Protein Name Cell division cycle-associated protein 3
Gene Name Name: CDCA3
Synonyms:C8,GRCC8,TOME1;
Organism Homo sapiens (Human)

PRO ID PR:Q99618
DAG View
PRO Name cell division cycle-associated protein 3 (human)
Definition A cell division cycle-associated protein 3 that is encoded in the genome of human.
Short Label hCDCA3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99618 (CDCA3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T10 Phosphorylation PhosphoSitePlus
R28 Methylation PhosphoSitePlus
S29 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S31 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
R36 Methylation PhosphoSitePlus
T37 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S43 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
S44 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
K59 Ubiquitination PhosphoSitePlus
S64 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 20068231
S68 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 17081983, ...18220336, 19651622, 18669648, 20068231
T70 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231, 18220336
T76 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
K79 Methylation PhosphoSitePlus
S82 Phosphorylation PhosphoSitePlus
S87 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 19664994, ...18669648, 19690332, 20068231
S94 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18578522, 23186163, 20058876, ...19651622, 20068231
T99 Phosphorylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
T159 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332
T161 Phosphorylation PhosphoSitePlus
S165 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332
S167 Phosphorylation PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
T177 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332
S181 Phosphorylation PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
S199 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 17081983, 18220336, ...19651622, 18669648, 19690332, 20068231
T202 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18220336
S209 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 17081983, ...18220336, 19651622, 18669648, 20068231
T212 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
T214 Phosphorylation PhosphoSitePlus
K219 Ubiquitination PhosphoSitePlus
S222 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
S229 Phosphorylation PhosphoSitePlus
K232 Ubiquitination PhosphoSitePlus
T239 Phosphorylation PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T76 K76 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S87 N87 Biomuta DOID:1324 / lung cancer [ cosmic ]
T159 K159 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S165 T165 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K219 E219 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]