iPTMnet Report for Q99615 (DNAJC7)
Protein Information
| UniProt AC / UniProt ID | Q99615 / DNJC7_HUMAN |
| Protein Name | DnaJ homolog subfamily C member 7 |
| Gene Name | Name: DNAJC7 Synonyms:TPR2,TTC2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q99615 |
| PRO Name | DnaJ homolog subfamily C member 7 (human) |
| Definition | A DnaJ homolog subfamily C member 7 that is encoded in the genome of human. |
| Short Label | hDNAJC7 |
| Category | organism-gene |
Q99615 (DNAJC7) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 22814378 | ||
| Y39 | Phosphorylation | score1 | phospho.ELM | 15592455 | ||
| K41 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K42 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y48 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y50 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y51 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K53 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K60 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R97 | Methylation | score1 | PhosphoSitePlus | |||
| K128 | Acetylation | score1 | PhosphoSitePlus | |||
| K128 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K137 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T151 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K155 | Acetylation | score1 | PhosphoSitePlus | |||
| K155 | Methylation | score1 | PhosphoSitePlus | |||
| K155 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C175 | S-Nitrosylation | score0 | dbSNO | 19483679 | ||
| K182 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S207 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C219 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| C225 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| R238 | Methylation | score1 | PhosphoSitePlus | |||
| K245 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C247 | Methylation | score1 | IEDB | 31844290 | ||
| K259 | Acetylation | score1 | PhosphoSitePlus | |||
| K268 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K273 | Acetylation | score1 | PhosphoSitePlus | |||
| K273 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K291 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K295 | Acetylation | score1 | PhosphoSitePlus | |||
| K295 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C298 | Methylation | score1 | IEDB | 31844290 | ||
| K306 | Acetylation | score1 | PhosphoSitePlus | |||
| K306 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K309 | Acetylation | score1 | PhosphoSitePlus | |||
| K309 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K322 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y327 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K329 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y355 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K359 | Acetylation | score1 | PhosphoSitePlus | |||
| K359 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K364 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K368 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K375 | Acetylation | score1 | PhosphoSitePlus | |||
| K375 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y382 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K384 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K390 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S393 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| R412 | Methylation | score1 | PhosphoSitePlus | |||
| K422 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K429 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K442 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S449 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y51 | C51 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| R97 | W97 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
| K182 | N182 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| K291 | Q291 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K295 | E295 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K384 | N384 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| R412 | W412 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] |
DAG View