Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99607 / ELF4_HUMAN
Protein Name ETS-related transcription factor Elf-4
Gene Name Name: ELF4
Synonyms:ELFR;
Organism Homo sapiens (Human)

PRO ID PR:Q99607
DAG View
PRO Name ETS-related transcription factor Elf-4 (human)
Definition An ETS-related transcription factor Elf-4 that is encoded in the genome of human.
Short Label hELF4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99607 (ELF4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K111 Sumoylation PhosphoSitePlus
T150 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648, 20068231
S151 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 23186163
S157 Phosphorylation HPRD   PhosphoSitePlus 19651622
S186 Phosphorylation HPRD   PhosphoSitePlus 17322306
T187 Phosphorylation HPRD   PhosphoSitePlus 19413330, 20068231
S188 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S194 Phosphorylation HPRD   PhosphoSitePlus 17322306
K230 Ubiquitination PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
Y262 Phosphorylation PhosphoSitePlus
R270 Methylation PhosphoSitePlus
Y272 Phosphorylation PhosphoSitePlus
Y273 Phosphorylation PhosphoSitePlus
K280 Sumoylation PhosphoSitePlus
K280 Ubiquitination PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
S369 Phosphorylation RLIMS-P 30890658
T527 Phosphorylation HPRD 20068231
K537 Ubiquitination PhosphoSitePlus
S641 Phosphorylation P45983 (MAPK8) HPRD   PhosphoSitePlus   RLIMS-P   UniProt 23186163, 20068231, 21465527, ...18452278
T643 Phosphorylation P24941 (CDK2) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P 16581786, 18669648
S648 Phosphorylation P24941 (CDK2) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 16581786, 18669648, 19690332, ...20068231
K657 Sumoylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K111 * Biomuta DOID:9256 / colorectal cancer [ tcga ]
S157 F157 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S157 Y157 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S194 N194 Biomuta DOID:363 / uterine cancer [ tcga ]
K245 N245 Biomuta DOID:1324 / lung cancer [ tcga ]
K249 T249 Biomuta DOID:1324 / lung cancer [ tcga ]
Y262 C262 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
R270 G270 Biomuta DOID:3571 / liver cancer [ icgc ]
Y272 C272 Biomuta DOID:5041 / esophageal cancer [ icgc ]
Y273 * Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
K291 T291 Biomuta DOID:1324 / lung cancer [ cosmic ]
K291 M291 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]